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| Effect of early enteral nutrition combined with parenteral nutrition sequential treatment for critical patients with mechanical ventilation |
| LI Ping1 WEN Jing1 NIE Yuqin2▲ |
1.Second Department of Intensive Care Medicine, Second Affiliated Hospital of Xinjiag Medical University, Xinjiang Uygur Autonomous Region, Urumqi 830028, China;
2. Department of Nursing, Second Affiliated Hospital of Xinjiag Medical University, Xinjiang Uygur Autonomous Region, Urumqi 830028, China |
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Abstract Objective To determine the effect of implementing early enteral nutrition combined with parenteral nutrition sequential treatment and outcomes of critical patients with mechanical ventilation. Methods From January to December 2016, in Second Department of Intensive Care Medicine of Second Affiliated Hospital of Xinjiag Medical University, according to random number table, 100 critical patients with mechanical ventilation support were divided into treatment group and control group, with 50 cases in each group. The control group was given total parenteral nutrition support, and the treatment group was treated with early enteral nutrition combined with parenteral nutrition sequential treatment, other treatment of two groups were same. Alb, PA, TRF, IgG, TST of patients were evaluated at admission and 14 d in hospital, ventilator associated pneumonia (VAP) of patients were observed, mechanical ventilation time, ICU stay time of patients in two groups were compared. Results After intervention, Alb, PA, TRF, IgG, TST of two groups were better than admission, and these of treatment group were better than control group, the differences were statistically significant (P < 0.05). The mechanical ventilation time, ICU stay time of treatment group were less than control group, rate of VAP in treatment group were less than control group, the differences were statistically significant (P < 0.05). Conclusion Early enteral nutrition combined with parenteral nutrition sequential treatment for critical patients with mechanical ventilation can improve nutritional status, regulate the immune function, reduce the prevalence of ventilator-associated pneumonia, shorten the mechanical ventilation time and hospitalization stay.
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