北京市某三级综合医院白细胞减少患者特征分析

Abstract
Figure/Table
References (22)
Related Citation (9)

Download: PDF (330 KB) HTML (1 KB)
Export: BibTeX | EndNote (RIS)

Abstract Objective To investigate the clinical features of leukopenia patients in a three level general hospital in Beijing. Methods Data of leukopenia patients, according to age, gender, distribution department, main symptoms in the hospital information management system (HIS) of Beijing Chuiyangliu Hospital Affiliated to Tsinghua University from July 2015 to July 2016 were collected and analyzed retrospectively. Results 3344 cases (12.36%) of leukopenia were found in 27 046 cases of patients with routine blood test, 1035 cases (30.59%) of men and 2309 cases (69.05%) of women. Outpatients accounted for 78.41% (2622 cases), 21.59% of hospitalized patients (722 cases). Among 722 hospitalized patients with leukopenia, neutropenia accounted for 97.65% (705 cases), 291 cases were male, accounting for about 41.28% of the total number of neutropenia, and 414 cases were female, accounting for about 58.72% of the total number of neutropenia; and agranulocytosis accounted for 1.94% (14 cases), there were 7 males, accounting for 50% of the total number of agranulocytosis, and 7 women, accounting for 50% of the total number of agranulocytosis. The hospitalized patients of leukopenia were mainly distributed in Department of Hematology, Department of Respiration, and Department of General Surgery. The outpatients with leukopenia were mainly distributed in Emergency Internal Medicine, Department of Respiration, and Department of Hematology. The hospitalized patients of neutropenia were mainly distributed in Department of Hematology, Department of Respiration, and Department of General Surgery. The hospitalized patients of agranulocytosis were mainly distributed in the Department of Respiration, ICU, Department of Hematology. Main symptoms of leucopenia outpatients were fever, cough, abdominal distension abdominal pain. Conclusion The incidence of leukopenia is high in a three lever general hospital, female more than male. Clinical symptoms are often atypical, and patients distribute in different departments. This should cause the attention of the doctors of the clinical departments.

Key words： Leukopenia Granulocytopenia Three level general hospital Clinical features

	Service

	E-mail this article
	Add to my bookshelf
	Add to citation manager
	E-mail Alert
	RSS
	Articles by authors
	YE Fang ZHANG Li'nan SUN Jianli WANG Huan TONG Chun WANG Ling

Cite this article:

YE Fang ZHANG Li'nan SUN Jianli WANG Huan TONG Chun WANG Ling. Analysis of clinical features of leukopenia patients in a three level general hospital in Beijing[J]. 中国医药导报, 2017, 14(14): 60-63.

URL:

http://www.yiyaodaobao.com.cn/EN/ OR http://www.yiyaodaobao.com.cn/EN/Y2017/V14/I14/60

[1] 张之南，沈悌.血液病诊断及疗效标准[M].3版.北京：科学技术出版社，2007：1-2.
[2] 蔡春颖.白细胞减少150例病因分析[J].中国临床医生杂志，2016，44（7）：72-74.
[3] 蒲玉春，阮淑芳.抗精神分裂药致白细胞减少的调查分析[J].深圳中西医结合杂志，2016（12）：67-69.
[4] 李志彬.探讨风湿免疫病血液系统损害的主要临床表现及其治疗手段[J].世界最新医学信息文摘，2016，16（1）：103-107.
[5] Matsuyama W，Yamamoto M，Higashimoto I，et al. TNF-related apoptosis-inducing ligand is involved in neutropenia of systemic lupus erythematosus [J]. Blood，2004，104（1）：184-191.
[6] 杨晶.探讨慢性乙型肝炎合并白细胞减少症的病因诊断及分析[J].中国社区医师：医学专业，2010，12（5）：60.
[7] 赵冬梅.正常体检人群外周血白细胞减少89例骨髓象分析[J].临床合理用药杂志，2015，8（8）：161-162.
[8] 王义霞，朱健康，黄燕.146例白细胞减少的病因探究[J].中国医学创新，2013，10（3）：140-141.
[9] 柳启传，刘璐璐，任艺.肝硬化患者中性粒细胞功能损伤的研究进展[J].世界华人消化杂志，2015，23（30）：4838-4843.
[10] 王觉生，郑素苹，周小玲.成都市白细胞减少症患病率的调查[J].中华医学杂志，1985，65（4）：160.
[11] 周红琳，王立茹.几种常见自身免疫性疾病血液学变化特点[J].中国实用内科杂志，2016，36（9）：806-809.
[12] 李志彬.探讨风湿免疫病血液系统损害的主要临床表现及其治疗手段[J].世界最新医学信息文摘：连续型电子期刊，2016，16（1）：103-107.
[13] 胡德忠，祝筱姬，张艳艳，等.C-反应蛋白与白细胞计数、血沉评估肺部感染早期疗效的对比研究[J].中国当代医药，2012，19（5）：8-10.
[14] Don M，Valent F，Canciani M，et al. Prediction of delayed recovery from pediatric community-acquired pneumonia [J]. Ital J Pediatr，2010，36（1）：51.
[15] Omer S，Zara O，Iacobescu C，et al. Partial splenic embolization for hypersplenism in cirrhotic patients.A case series [J]. J Gastrointestin Liver Dis，2014，23（2）：215-218.
[16] Sheehan VA，Weir A，Waters B. Hepatitis C and neutropenia [J]. Curr Opin Hematol，2014，21（1）：58-63.
[17] 张荣金，郝咏梅.弥漫性毒性甲状腺肿患者白细胞减少/缺乏的机制及治疗[J].临床荟萃，2016，31（3）：246-249.
[18] 何珂，朱丽华，陆西宛.初诊断Graves病患者白细胞或中性粒细胞减少与TRAb相关性研究[J].免疫学杂志，2016，32（7）：611-615.
[19] Takata K，Kubota S，Fukata S，et al. Methimazole-induced agranulocytosis in patients with Graves' disease is more frequent with an initial dose of 30 mg daily than with 15 mg daily [J]. Thyroid，2009，19（6）：559-563.
[20] 熊丹，李末娟，吴东红，等.59例恶性血液病患者合并侵袭性真菌病的临床分析[J].中国医药科学，2016，6（5）：18-21，25.
[21] 邱艳，李长英.肿瘤化疗患者白细胞减少并发感染的危险因素及预防对策[J].实用临床医药杂志，2016，20（9）：57-59，63.
[22] 王欣，刘泽林，卢博，等.血液病性贫血患者红细胞参数的分布规律及其相互关系[J].中国医药科学，2015，5（14）：171-173.