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Short-term prognostic analysis of elderly patients with acute inferior myocardial infarction with different infarct-related artery after primary PCI |
LI Chenggang1 XIA Yong2 GAO Wen1 TONG Jiangtao1 |
1.Institute of Cardiovascular Disease, Xuzhou Medical University, Jiangsu Province, Xuzhou 221000, China;
2.Department of Cardiology, Affiliated Hospital of Xuzhou Medical University, Jiangsu Province, Xuzhou 221000, China |
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Abstract Objective To investigate the elderly patients' short-term clinical prognosis of acute inferior wall ST-segment elevation myocardial infarction (STEMI) with different infarct-related artery (IRA) undergoing primary percutaneous coronary intervention (pPCI). Methods From January 2015 to April 2016, in Department of Cardiology of Affiliated Hospital of Xuzhou Medical University, 133 elderly patients (≥60 years) with the inferior wall STEMI undergoing pPCI successfully were selected. According to difference of IRA, the enrolled elderly patients were divided into rightcoronary artery group (RCA group, n = 103) and left circumflex group (LCX group, n = 30). The patients' general clinical characteristic, and all patients followed up within 30 d of major adverse cardiovascular events (MACE), including cardiacdeath, heart failure or cardiogenic shock, malignant arrhythmia and target vessel revascularization were collected. Results LVEF of RCA group after operation 7 d and follow-up 30 d were significantly lower than those of LCX group [(47.1±8.4)% vs (53.4±7.1)%, (49.5±8.9)% vs (56.3±6.9)%,], the differences were statistically significant (P < 0.05). During the follow-up period, there were 45 MACE case in the group RCA, only 6 MACE cases in the group LCX. incidence of MACE in two groups was compared (43.7% vs 20.0%), the difference was statistically significant (P < 0.05). Conclusion RCA induced inferior STEMI in elderly patients has a poorer short-term prognosis than LCX.
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[1] 中华医学会心血管病学分会,中华心血管病杂志编辑委员会.急性ST段抬高型心肌梗死诊断和治疗指南[J].中华心血管病杂志,2015,43(5):380-393.
[2] European Society of Cardiology. ESC Guidelines for the management of acute myocardial infarction in patients presistent with ST-segment elevation [J]. Eur heart J,2012,33(20):2569-2619.
[3] National Clinical Guideline Centre (UK). The acute management of myocardial infarction with ST-segment elevation [S]. London:Royal College of Physicians (UK),2013.
[4] American College of Cardiology. 2015 ACC/AHA/SCAI focused update on primary percutaneous coronary intervention for patients with ST-elevation myocardial infarction:an update of the 2011 ACCF/AHA/SCAI Guideline for percutaneous coronary intervention and the 2013 ACCF/AHA Guideline for the management of ST-elevation myocardial infarction [J]. Circulation,2016,133(11):1135-1147.
[5] Stone PH,Raabe DS,Jaffe AS,et al. Prognostic significance of location and type of myocardial infarction: ndependent adverse outcome associated with anterior location [J]. J Am Coll Cardiol,1988,11(3):453-463.
[6] White HD,Thygesen K,Alpert JS,et al. Clinical implications of the third universal definition of myocardial infarction [J]. Heart,2014,100(5):424-432.
[7] PontecorvoML,SpazianiC,MontoneRA,et al. Myocardial noreflowphenomenon:recentknowledges [J]. Recenti Prog Med,2011,102(2):53-57.
[8] Durante A,Camici PG. Novel insights into an "old" phenomenon: the no reflow [J]. Int J Cardiol,2015,187(1),273-280.
[9] Chhapra DA,Mahajan SK,Thorat ST. A study of the clinical profile of right ventricular infarction in context to inferior wall myocardiainfarctionina tertiary care centre [J]. J Cardiovasc Dis Res,2013,4(3):170-176.
[10] 代政学,张敏,李金明,等.不同罪犯血管引起的急性下壁心肌梗死临床特点[J].中国循证心血管医学杂志,2015, 7(3):307-308,312.
[11] 杨芳,彭春花,卢静,等.急性下壁心肌梗死心电图表现与冠状动脉造影的对比分析[J].昆明医科大学学报,2013, 34(2):69-70,86.
[12] 廖祁伟,光雪峰,景舒南,等.急性ST段抬高型心肌梗死并发心源性休克的相关危险因素分析[J].昆明医科大学学报,2013,34(2):91-95,116.
[13] Jacobs AK,Leopold JE,Mendes LA,et al. Cardiogenic shock caused by right ventriculairinfarction:a report from the SHOCK registry [J]. J Am Coll Cardiol,2003,41(8):12731279.
[14] Ventetuolo CE,Klinger JR. Management of acute right ventricular failure in the intensive care unit [J]. Ann Am Thorac Soc,2014,11(5):811-822.
[15] Kruk M,Buller CE,Tcheng JE,et al. Impact of left ventricular ejection fraction on clinical outcomes over five years after infarct- related coronary artery recanalization(from the occluded artery trial[OAT]) [J]. Am J Cardiol,2010,105(1):10-16.
[16] 王玉兰,张英.希望护理模式对老年冠心病患者行PCI治疗前焦虑抑郁情绪的影响[J].中国医学装备,2016, 13(2):101-103.
[17] 刘洁茹,王菊文.比伐卢定和普通肝素在STEMI患者PCI术中对凝血功能的影响及安全性比较[J].中国现代医生,2015,53(20):86-88,92.
[18] 禹子清,彭娟,樊冰.急性ST段抬高型心肌梗死患者发生高危室性心律失常的相关危险因素分析[J].中国临床医学,2015,22(4):486-490.
[19] 李贵森.急诊PCI术前强化他汀药物治疗对急性ST段抬高型心肌梗死患者预后的影响[J].中国医药导报,2015, 12(8):65-69.
[20] 李伟山,刘兆平,李建平.急性心肌梗死患者直接经皮冠状动脉介入治疗疗效与预后的影响因素[J].中国介入心脏病学杂志,2008,16(1):8-11. |
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