|
|
Clinical value of early interventional therapy with fiberoptic bronchoscopy in children with Mycoplasma pneumoniae pneumonia complicated with airway mucus embolism |
TAO Pei XIA Wanmin |
Department of Children′s Respiratory, Chengdu Women′s and Children′s Central Hospital, Sichuan Province, Chengdu 610091, China |
|
|
Abstract Objective To investigate the clinical value of early interventional therapy with fiberoptic bronchoscopy in children with Mycoplasma pneumoniae pneumonia (MPP) complicated with airway mucus embolism. Methods Clinical data of 92 MPP children complicated with airway mucus embolism in Department of Children′s Respiratory of Chengdu Women's and Children′s Central Hospital from February 2015 to February 2017 A retrospective, they were grouped according to the course of disease that from admission to fiberoptic bronchoscopy interventional therapy, children with the course of disease more than 10 days were defined as the control group (45 cases) and whose the course of disease less than or equal to 10 days were defined as the observation group (47 cases). The therapeutic effects of the two groups were compared and analyzed. Results The duration of fever, hospitalization, recovery time of white blood cell count and C-reactive protein in the observation group were significantly shorter than those in the control group, the differences were highly statistically significant (P < 0.01). There was statistically significant difference in the proportion of children with 60%-90% pulmonary consolidation absorption area 1, 3 months after treatment (P < 0.05); the pulmonary consolidation absorption areas of children in the observation group 1, 2, 3 months after treatment were better than those in the control group, the differences were statistically significant (P < 0.05). The incidence of atelectasis in the observation group was significantly lower than that in the control group 1, 2, 3 months after treatment, the differences were statistically significant (P < 0.05). Conclusion Early intervention of fiberoptic bronchoscopy in the treatment of MPP patients with airway obstruction with intraairway mucus embolism has a good safety and high clinical value, which is worthy of clinical promotion.
|
|
|
|
|
[1] 尹立岩.肺炎支原体导致小儿下呼吸道感染的临床特征研究[J].中国医药导刊,2014,10(2):217-218.
[2] 袁槿,赵涛,刘亚锋.纤支镜灌洗疗法在儿童重症支原体肺炎中的应用及其发热期疗效观察[J].临床肺科杂志,2016,21(7):1233-1236.
[3] 苏宇飞,常文毅,王列,等.纤维支气管镜下支气管肺泡灌洗治疗儿童重症支原体肺炎的疗效探讨[J].中国妇幼健康研究,2016,27(1):58-61.
[4] 胡亚美,江载芳.诸福堂实用儿科学[M].7版.北京:人民卫生出版社,2002:1204-1205.
[5] 陈璐,陈艳萍,黄建宝,等.布地奈德联合盐酸氨溴索雾化吸入对小儿肺炎支原体感染所致慢性咳嗽的影响[J].实用临床医药杂志,2014,18(3):66-67.
[6] 楼兰芳,李小兵,张兰青.小儿肺炎支原体感染后血清免疫球蛋白、红细胞免疫及外周血T淋巴细胞亚群的变化情况分析[J].中国妇幼保健,2015,30(3):385-387.
[7] 吴倩.儿童肺炎支原体感染流行病学的研究进展[J].中国妇幼保健,2016,31(5):1111-1114.
[8] 梅玉霞,丁立人,庄承,等.儿童难治性支原体肺炎诊治进展[J].上海交通大学学报:医学版,2015,35(2):286-290.
[9] 韩丽娜.儿童重症/难治性肺炎支原体肺炎的治疗进展[J].国际儿科学杂志,2018,45(2):100-105.
[10] 朱柏辉.电子支气管镜灌洗介入治疗支原体肺炎伴肺不张患儿的临床疗效[J].中国妇幼保健,2018,33(10):2376-2379.
[11] 刘清彪,罗慧嫦,许柏华,等.纤维支气管镜下支气管肺泡灌洗治疗儿童重症支原体肺炎的效果观察[J].中国当代医药,2017,24(25):107-109.
[12] 高庆林,付瑜.纤维支气管镜下支气管肺泡灌洗治疗重症肺部感染的临床效果[J].中国当代医药,2019,26(9):88-90.
[13] Saraya T,Kurai D,Nakagaki K,et al. Novel aspects on the pathogenesis of Mycoplasma pneumoniae pneumonia and therapeutic implications [J]. Frontiers in Microbiology,2014,5(410):410-413.
[14] 刘晓青,黎毅敏,何为群,等.纤维支气管镜在低咳嗽峰流速慢性阻塞性肺疾病急性加重期患者拔管后的应用[J].中华危重病急救医学,2014,12(12):855-859.
[15] 李东,范丽萍,孙惠泉,等.儿童肺炎支原体肺炎合并肺不张临床特点及纤维支气管镜的诊疗分析[J].中国小儿急救医学,2014,21(8):489-492.
[16] 曹丽洁,刘建华,帅金凤.纤维支气管镜早期介入治疗对气道内黏液栓阻塞的儿童肺炎支原体肺炎的价值[J].中国当代儿科杂志,2018,20(4):17-18.
[17] 陈聪,余春梅,陈静.塑型性支气管炎的诊治进展[J].检验医学与临床,2014,10(12):1712-1713.
[18] 王丽萍,陈守平,黄玉瑛.软式支气管镜在儿童呼吸系统疾病中的应用[J].中国当代儿科杂志,2017,19(11):1174-1179.
[19] 任宾,张宏广.纤维支气管镜治疗微创肺癌切除术后排痰不畅和肺不张的临床研究[J].山西医药杂志,2014, 17(8):931-933.
[20] 李挺.纤支镜灌洗与常规治疗重症肺部感染合并肺不张137例对比分析[J].临床肺科杂志,2015,15(6):1105-1107. |
|
|
|