|
|
|
| Clinical effect of herbal fumigation and washing therapy of Zhuang medicine on chronic abacterial prostatitis |
| ZHU Min1 LU Zhihua2 DAI Fang1 HUANG Cunchao1 JIANG Jianling2 MAI Pengyu2 LIU Ying1 |
| 1.Department of Andrology, Ruikang Hospital Affiliated to Guangxi University of Chinese Medicine, Guangxi Zhuang Autonomous Region, Nanning 530011, China; 2.Graduate School, Guangxi University of Chinese Medicine, Guangxi Zhuang Autonomous Region, Nanning 530001, China |
|
|
|
Abstract Objective To observe the clinical effect of herbal fumigation and washing therapy of Zhuang medicine on chronic abacterial prostatitis (CAP). Methods 160 CAP patients from January 2015 to August 2016 in Ruikang Hospital Affiliated to Guangxi University of Chinese Medicine were randomly divided into treatment group and control group with 80 cases in each group by using random number table method. Treatment group was fumigated and washed with Qianlieshu external lotion, while control group was intervened with Qianlie′an Suppository. Both groups were treated with 28 days as a course of treatment. After one course of treatment, clinical total effective rate was compared between two groups. NIH-CPSI score, TCM syndrome score and levels of interleukin (IL)-2, IL-8 and IL-10 in prostatic fluid were compared between two groups before and after treatment. Results After treatment, total effective rate of treatment group was higher than that of control group (P < 0.05). After treatment, the scores of NIH-CPSI and TCM syndromes in two groups were lower than those before treatment (P < 0.05), and the scores in treatment group were lower than those in control group (P < 0.05). After treatment, the level of IL-8 in prostatic fluid of two groups was lower than that before treatment (P < 0.05), and the level of IL-8 in treatment group was lower than that in control group (P < 0.05). After treatment, the levels of IL-2 and IL-10 in prostatic fluid of both groups were higher than before treatment (P < 0.05), and treatment group was higher than control group (P < 0.05). Conclusion The fumigation and washing therapy of Zhuang medicine has better effect on CAP. This method can reduce the level of IL-8 in prostatic fluid and increase the levels of IL-2 and IL-10 in prostatic fluid. This may be one of the mechanisms of herbal fumigation and washing therapy for CAP in Zhuang medicine.
|
|
|
|
|
|
[1] 中国中西医结合学会男科专业委员会.慢性前列腺炎中西医结合诊疗专家共识[J].中国中西医结合杂志，2015， 35（8）：933-941.
[2] 李海松，王彬，赵冰.慢性前列腺炎中医诊治专家共识[J].北京中医药，2015，34（5）：412-415.
[3] 蒋永康.血清总前列腺特异性抗原检测在慢性前列腺炎诊断中的应用价值[J].中国医药导报，2017，14（7）：114-116，120.
[4] 张春雷，刘成.慢性非细菌型前列腺炎治疗的相关进展[J].中国医药导报，2015，12（10）：38-42.
[5] 郑筱萸.中药新药临床研究指导原则（试行）[M].北京：中国医药科技出版社，2002：168-172.
[6] 庞宇舟，林辰，黄冬玲.壮医药学概论[M].南宁：广西民族出版社，2006：44-45.
[7] 唐汉庆，黄岑汉，赵玉峰，等.壮医“三道两路”理论的辨析及应用[J].中华中医药杂志，2015，30（5）：4236-4239.
[8] 朱闽，徐楠，荀建宁，等.湿热消腰部热敷疗法对EAP模型前列腺Th17细胞相关因子表达的影响[J].辽宁中医杂志，2018，45（1）：198-202.
[9] 朱闽，荀建宁，覃兆伟，等.壮药前列舒外洗剂治疗慢性前列腺炎的临床研究[J].西部中医药，2015，28（8）：57-59.
[10] 尹震花，张娟娟，陈林，等.了哥王化学成分与生物活性研究进展[J].中草药，2018，49（8）：1964-1976.
[11] 徐丽丽，徐一，郭秋言，等.杠板归的研究进展[J].中医药导报，2017，23（24）：118-122.
[12] 林紫微，赵智萍，林志军，等.海南三叉苦抗炎作用及机制研究[J].海南医学，2016，27（13）：2079-2081.
[13] 左芙蓉.绞股蓝多糖对免疫抑制小鼠免疫功能的影响[D].南宁：广西大学，2017.
[14] 梁启成，钟鸣.中国壮药学[M].南宁：广西民族出版社，2005：83-337.
[15] 郑小挺，陈东，尹申，等.前列腺液中白细胞计数对慢性前列腺炎症状程度的影响[J].中华中医药学刊，2016， 34（8）：1914-1916.
[16] 孙自学，李鹏超.慢性前列腺炎的中西医结合治疗思路[J].辽宁中医杂志，2018，45（2）：289-291.
[17] 杨武斌.针灸为主的临床治疗方案在慢性前列腺炎患者中的效果[J].中国医药科学，2017，7（1）：70-73.
[18] 万涛，周治军，卢童，等.复方玄驹胶囊治疗慢性前列腺炎的临床疗效及对血清MIP-2 SIgA水平的影响[J].河北医学，2018，24（6）：894-897.
[19] Schaeffer EM. Re：Th1-Th17 cells contribute to the development of uropathogenic Escherichia coli-induced chronic pelvic pain [J]. PLoS One，2014，191（6）：1808-1809.
[20] 丁劲，张耀圣，闫博，等.除湿通淋颗粒治疗慢性非细菌性前列腺炎临床疗效及对IL-2、IL-6、IL-8影响观察[J].中国性科学，2015，24（5）：82-85.
[21] 尤传静，吴强.中药清浊汤对ⅢB型前列腺炎湿热瘀阻症患者SIgA、IL-8、TNF-α的影响[J].中国男科学杂志，2017，31（2）：47-50.
[22] 桂金勇，童宏华，杨巧英.左氧氟沙星联合银花泌炎灵治疗慢性前列腺炎的效果及对血清IL-10、hs-CRP、TNF-α的影响[J].广东医学，2018，39（23）：3569-3572. |
|
|
|
