上海城乡结合地区老年轻度认知功能障碍筛查及相关因素分析

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Abstract Objective To investigate the prevalence rate and influencing factors of mild cognitive impairment (MCI) among the elderly in urban and rural areas of Shanghai. Methods According to the age stratification, the elderly in the same community was selected randomly. From September to November 2018, the cognitive function of residents in the Outpatient Department of Community Health Service Center and the Activity Center of Neighborhood Committee was investigated, as well as the general information, including gender, educational year, age, family structure, smoking history, drinking history, drink, religious belief, coronary heart disease history, hypertension history, diabetes history. The prevalence rate and risk factors were analyzed by the generalized MCI method. Results A total of 554 people were investigated effectively, and 73 cases were screened for MCI (MCI group), with a prevalence rate of 13.2%. The prevalence of MCI was 8.2% for those aged 60-64 years old, 9.5% for those aged >64-69 years old, 14.7% for those aged >69-74 years old, 23.5% for those aged >74-79 years old, 25.7% for those aged >79-84 years old, and 27.3% for those aged >84 years old, respectively, the remaining 481 cases were in the normal group. Univariate analysis showed that there were no significant differences in gender, smoking, alcoholism, drink and religious beliefs between the MCI group and the normal group (P ＞ 0.05); there were highly statistically significant differences in educational year, age and coronary heart disease between the two groups (P ＜ 0.01); there were statistically significant differences in family structure, hypertension and diabetes between the two groups (P ＜ 0.05). Multiple Logistic regression analysis showed that, advanced age (OR = 1.08, 95%CI: 1.03-1.13, P ＜ 0.01), smoking (OR = 2.83, 95%CI: 1.11-7.16, P ＜ 0.05), coronary heart disease (OR = 2.11, 95%CI: 1.19-3.73, P ＜ 0.05), hypertension (OR = 2.21, 95%CI: 1.17-4.18, P ＜ 0.05), diabetes (OR = 1.78, 95%CI: 1.02-3.11, P ＜ 0.05) were all risk factors for MCI disease. High educational level (OR = 0.82, 95%CI: 0.75-0.91, P ＜ 0.01) was the protective factor of MCI disease. Conclusion It is helpful to reduce the prevalence rate of MCI by strengthening the prevention and control of the elderly, smokers, people with low education level, and people with coronary heart disease, hypertension and diabetes.

Key words： The elderly Mild cognitive impairment Epidemiological survey Prevalence rate Risk factor

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	LIU Jialu1 YU Dehua1
	2 LU Yuan1
	2 WANG Hao1
	3

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LIU Jialu1 YU Dehua1,2 LU Yuan1,2 WANG Hao1, et al. Screening of mild cognitive impairment among the elderly in urban and rural areas of Shanghai and analysis on its related factors[J]. 中国医药导报, 2019, 16(24): 62-66.

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http://www.yiyaodaobao.com.cn/EN/ OR http://www.yiyaodaobao.com.cn/EN/Y2019/V16/I24/62

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