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| Refinement of fine needle aspiration cytological morphologic criteria of papillary thyroid carcinoma |
| WANG Yunhong1 SHI Xiaolan2 GUO Juan3 YU Xiaomeng1▲ |
1.Department of Pathologic, Beijing Friendship Hospital, Beijing 100059, China;
2.Department of Pathologic, the Second People′s Hospital of Liaocheng, Shandong Province, Liaocheng 252600, China;
3.Department of Pathologic, the Second Hospital of Xiamen, Fujian Province, Xiamen 361021, China |
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Abstract Objective To validate the efficiency of the cytological diagnostic criterion of papillary thyroid carcinoma (PTC) defined by of Beijing Friendship Hospital ("BFH" for short). Methods All thyroid fine needle aspiration (FNA) cases with histological results of PTC were reviewed from March 2015 to December 2016 by Nikiforov′s, Kini′s and BFH′s cytological diagnostic criterias of PTC. The sensitivities and specificities of 3 criterias were calculated with histological results as the gold standard. Results Total 339 thyroid FNA cases with histological results as control were reviewed, including 337 cases of PTC. With definite diagnosis as positive standard, the sensitivities of 3 kinds of PTC FNA cytological diagnostic criteria was 86.9% (219/337), 34.1% (115/337) and 65.0% (219/337), respectively. The specificities were all 100%. The sensitivity of BFH criterion increased 52.8% and 21.9% compared with Nikiforov and Kini criterion. Conclusion The BFH′s PTC cytologic diagnostic criterion has highly sensitive, specific and worthy of the recommendation.
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