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| Clinical effect of external washing of Jieyou Decoction in the treatment of diabetic foot |
| SHI Wen HAN Hong |
| Department of Traditional Chinese Medicine, Beijing Sixth Hospital, Beijing 100007, China |
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Abstract Objective To explore the clinical effect of external washing of Jieyou Decoction in the treatment of diabetic foot. Methods Total of 99 cases of patients with diabetic foot met with the diagnostic criteria of Chinese and Western medicine in Department of Traditional Chinese Medicine of Beijing Sixth Hospital from January 2016 to June 2017 were selected. They were divided into treatment group and control group by 2∶1 through random number table method, with 66 cases in the treatment group and 33 cases in the control group. A total of 93 patients were included in this study, including 63 cases in the treatment group and 30 cases in the control group. The treatment group was taken external washing of Jieyou Decoction, the control group was treated with 5% Elikey Povidone Iodine Solution and washed with a 1∶5 dilution of 3000 mL. The curative effect, wound healing rate at different time points and adverse reactions of the two groups were compared. Followed up for half a year, the incidence of grade 4 to 5 of Wagner grading in the two groups was observed. Results The curative effect of treatment group was better than that of control group, the difference was highly statistically significant (P ＜ 0.01). There was no significant difference of the wound healing rate between the two groups at the 2nd and 4th week (P ＞ 0.05), while the wound healing rates of the treatment group were higher than thoes of the control group at the 6th and 8th week, the differences was statistically significant (P ＜ 0.05). Followed up for half a year, the incidence of grade 4 to 5 of Wagner grading in the control group was higher than the treatment group, the differences were statistically significant (P ＜ 0.05). No obvious adverse reactions were observed during the treatment. Conclusion The external washing of Jieyou Decoction has obvious healing effect for diabetic foot, which can effectively control the development of ulcer of diabetic foot.
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[1] 薛耀明，邹梦晨.中国糖尿病足防治指南（2019版）解读[J].中华糖尿病杂志，2019，11（2）：88-91.
[2] 中华医学会糖尿病学分会.中国2型糖尿病防治指南（2013年版）[J].中华糖尿病杂志，2014，6（7）：447-498.
[3] 常宝成，潘从清.糖尿病足的诊断和治疗[J].国外医学：内分泌学分册，2002，22（1）：25.
[4] 范丽凤，陆菊明，郑亚光，等.糖尿病足溃疡的文献因素分析[J].中国糖尿病杂志，2005，13（2）：129-130.
[5] 许樟荣.糖尿病足病变的分类与诊治进展[J].内科急危重症杂志，2002，8（1）：32-35.
[6] 中国医疗保健国际交流促进会糖尿病足病分会.中国糖尿病足诊治指南[J].中华医学杂志，2017，97（4）：251-258.
[7] 中华医学会糖尿病学分会.中国2型糖尿病防治指南（2017年版）[J].中华糖尿病杂志2018，10（1）：4-67.
[8] 中华中医药学会糖尿病分会.糖尿病足中医诊疗标准[J].世界中西医结合杂志，2011，6（7）：618-625.
[9] 李曰庆，何清湖.中医外科[M].北京：中国中医药出版社，2012：295.
[10] 秦世霞.脱疽的中医护理[J].航空航天医学杂志，2011， 22（8）：993-994.
[11] 中华人民共和国卫生部.中药新药临床研究指导原则[S].2002.
[12] 蒋其霞.伤口护理临床实践指南[M].南京：东南大学出版社，2004：75.
[13] 张靖航，王鹏华，褚月颉，等.糖尿病足溃疡感染多重耐药铜绿假单胞菌的危险因素及预后分析[J].中国糖尿病杂志，2014，22（12）：1095-1097.
[14] 李丹，陈龙菊.糖尿病足神经病变动物模型研究进展[J].中国实验动物学报，2018，26（1）：128-132.
[15] 黄海峰.糖尿病足住院老年患者的临床特点及截肢相关因素分析[J].中国医药科学，2018，8（23）：197-200.
[16] 张贺成，魏苏.糖尿病周围神经病变诊断进展[J].中国医药导报，2017，14（2）：45-48.
[17] 韩明姬.糖尿病足的中西医结合治疗[J].中医临床研究，2014，6（3）：90-91.
[18] 袁向明.分期辨证治疗糖尿病足32例疗效分析[J].中医药通报，2009，8（6）：44-46.
[19] 周岗，李海红，付小兵.糖尿病足溃疡的研究现状[J].中国临床康复，2004，8（33）：7540-7541.
[20] 唐宝康.不同程度感染的糖尿病足溃疡患者临床特点及预后分析[J].中国实用医药，2018，13（33）：86-87.
[21] 郭凯，何泱，许蕾，等.糖尿病足溃疡患者耐药大肠埃希菌感染的临床特点与相关危险因素分析[J].临床内科杂志，2016，33（10）：690-693.
[22] 郑孝宏.糖尿病足的外洗治疗[J].中国营养保健，2018， 28（15）：252.
[23] 张润玲，王琴，张赟.中药外洗治疗辅助治疗糖尿病足25例[J].陕西中医，2005，26（10）：1054-1055.
[24] 马天红，潘孙峰，方瑞华，等.活血解毒方外洗治疗初期糖尿病足伴溃疡26例观察[J].浙江中医杂志，2007，52（1）：18-19. |
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