lncRNA与糖尿病心肌缺血再灌注关系的研究进展

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Abstract lncRNA is a member of the non-coding RNA family. Due to the development of biochip and sequencing technology, lncRNA does not have the function of encoding proteins, but its biological effects are constantly demonstrated. lncRNAs and miRNAs are coupled with each other and produce a clear effect in a number of pathological processes. Diabetic myocardial ischemic diseasesare the focus of perioperative prevention and treatment. lncRNAs are closely related to the occurrence and development of diabetic myocardial ischemia-reperfusion. This paper mainly describes the research progress on the relationship between the biological effects of lncRNA and ischemia-reperfusion of diabetic cardiomyopathy.

Key words： Diabetes mellitus Myocardial ischemia/reperfusion Non-coding RNA lncRNA

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	LI Wenyuan LI Wei LENG Yan XIONG Yonghong XIA Zhongyuan▲

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LI Wenyuan LI Wei LENG Yan XIONG Yonghong XIA Zhongyuan▲. Research progress on relationship between long noncoding RNA and diabetic myocardial ischemia/reperfusion injury[J]. 中国医药导报, 2019, 16(22): 50-53.

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http://www.yiyaodaobao.com.cn/EN/ OR http://www.yiyaodaobao.com.cn/EN/Y2019/V16/I22/50

[1] Alam U，Asghar O，Azmi S，et al. General aspects of diabetes mellitus [J]. Handb Clin Neurol，2014，126：211-222. doi：10.1016/B978-0-444-53480-4.00015-1. PMID：25410224.
[2] Ogurtsova K，da Rocha Fernandes JD，Huang Y，et al. IDF Diabetes Atlas: Global estimates for the prevalence of diabetes for 2015 and 2040 [J]. Diabetes Res Clin Pract，2017，128：40-50. doi：10.1016/j.diabres.2017.03.024. PMID：28437734.
[3] Hua F，Yu JJ，Hu ZW. Diabetes and cancer，common threads and missing links [J]. Cancer Lett，2016，374（1）：54-61. doi：10.1016/j.canlet.2016.02.006. PMID：26879686.
[4] Ferdinandy P，Hausenloy DJ，Heusch G，et al. Interaction of risk factors，comorbidities，and comedications with ischemia/reperfusion injury and cardioprotection by preconditioning, postconditioning，and remote conditioning [J]. Pharmacol Rev，2014，66（4）：1142-1174. doi：10.1124/pr.113.008300. PMID：25261534.
[5] Benjamin EJ，Virani SS，Callaway CW，et al. Heart disease and stroke statistics-2018 update：a report from the American Heart Association [J]. Circulation，2018，137（12）：e67-e492. doi：10.1161/CIR.0000000000000558. PMID：29386200.
[6] Buntaine AJ，Shah B，Lorin JD，et al. Revascularization strategies in patients with diabetes mellitus and acute coronary syndrome [J]. Curr Cardiol Rep，2016，18（8）：79. doi：10.1007/s11886-016-0756-3. PMID：27339854.
[7] Dehghani R，Rahmani F，Rezaei N. MicroRNA in Alzheimer′s disease revisited：implications for major neuropathological mechanisms [J]. Rev Neurosci，2018，29（2）：161-182. doi：10.1515/revneuro-2017-0042. PMID：28941357.
[8] Ma C，Luo H，Liu B，et al. Long noncoding RNAs：a new player in the prevention and treatment of diabetic cardiomyopathy? [J]. Diabetes Metab Res Rev，2018，34（8）：e3056. doi：10.1002/dmrr.3056. PMID：30160026.
[9] Dangwal S，Schimmel K，Foinquinos A，et al. Noncoding RNAs in heart failure [J]. Handb Exp Pharmacol，2017，243：423-445. doi：10.1007/164_2016_99. PMID：27995387.
[10] Ferrero S，Evangelisti G，Barra F. Current and emerging treatment options for endometriosis [J]. Expert Opin Pharmacother，2018，19（10）：1109-1125. doi：10.1080/14656566.2018.1494154. PMID：29975553.
[11] Sachani SS，Landschoot LS，Zhang L，et al. Nucleoporin 10762 and 153 mediate Kcnq1ot1 imprinted domain regulation in extraembryonic endoderm stem cells [J]. Nat Commun，2018，9（1）：2795. doi：10.1038/s41467-018-05208-2. PMID：6052020.
[12] Kleaveland B，Shi CY，Stefano J，et al. A network of noncoding regulatory RNAs acts in the mammalian brain [J]. Cell，2018，174（2）：350.e317-362.e317. doi：10.1016/j.cell.2018.05.022. PMID：29887379.
[13] Li Y，Egranov SD，Yang L，et al. Molecular mechanisms of long noncoding RNAs-mediated cancer metastasis [J]. Genes Chromosomes Cancer，2018. [Epub ahead of print]. doi：10.1002/gcc.22691. PMID：30350428.
[14] Saeedi Borujeni MJ，Esfandiary E，Taheripak G，et al. Molecular aspects of diabetes mellitus：resistin，microRNA，and exosome [J]. J Cell Biochem，2018，119（2）：1257-1272. doi：10.1002/jcb.26271. PMID：28688216.
[15] Ju C，Sheng Z，Wang Q，et al. Advanced glycation end products of bovine serum albumin affect the cell growth of human umbilical vein endothelial cells via modulation of MEG3/miR-93/p21 pathway [J]. Acta Biochim Biophys Sin （Shanghai），2018. [Epub ahead of print]. doi：10.1093/abbs/gmy147. PMID：30544204.
[16] Yu JL，Li C，Che LH，et al. Downregulation of long noncoding RNA H19 rescues hippocampal neurons from apoptosis and oxidative stress by inhibiting IGF2 methylation in mice with streptozotocin-induced diabetes mellitus [J]. J Cell Physiol，2018. [Epub ahead of print]. doi：10.1002/jcp.27746. PMID：30536889.
[17] Erfanian Omidvar M，Ghaedi H，Kazerouni F，et al. Clinical significance of long noncoding RNA VIM-AS1 and CTBP1-AS2 expression in type 2 diabetes [J]. J Cell Biochem，2018. [Epub ahead of print]. doi：10.1002/jcb.28206. PMID：30506719.
[18] Li Q，Pang L，Yang W，et al. Long non-coding RNA of myocardial infarction associated transcript （lncrna-miat） promotes diabetic retinopathy by upregulating transforming growth factor-beta1 （tgf-beta1） signaling [J]. Med Sci Monit，2018，24：9497-9503. doi：10.12659/MSM.911787. PMID：30595603.
[19] Luo H，Wang J，Liu D，et al. The lncRNA H19/miR-675 axis regulates myocardial ischemic and reperfusion injury by targeting PPARalpha [J]. Mol Immunol，2018，105：46-54. doi：10.1016/j.molimm.2018.11.011.
[20] Hang P，Zhao J，Su Z，et al. Choline inhibits ischemia-reperfusion-induced cardiomyocyte autophagy in rat myocardium by activating Akt/mTOR signaling [J]. Cell Physiol Biochem，2018，45（5）：2136-2144. doi：10.1159/000488049. PMID：29533930.
[21] Chen ZL，Liu RS，Niu QX，et al. Morphine postconditioning alleviates autophage in ischemia-reperfusion induced cardiac injury through up-regulating lncRNA UCA1 [J]. Biomed Pharmacother，2018，108：1357-1364. doi：10.1016/j.biopha.2018.09.119. PMID：30372838.
[22] Li X，Du N，Zhang Q，et al. MicroRNA-30d regulates cardiomyocyte pyroptosis by directly targeting foxo3a in diabetic cardiomyopathy [J]. Cell Death Dis，2014，5：e1479. doi：10.1038/cddis.2014.430. PMID：4237254.
[23] Yang F，Qin Y，Wang Y，et al. LncRNA KCNQ1OT1 mediates pyroptosis in diabetic cardiomyopathy [J]. Cell Physiol Biochem，2018，50（4）：1230-1244. doi：10.1159/000494576. PMID：30355944.
[24] Qi K，Zhong J. LncRNA HOTAIR improves diabetic cardiomyopathy by increasing viability of cardiomyocytes through activation of the PI3K/Akt pathway [J]. Exp Ther Med，2018，16（6）：4817-4823. doi：10.3892/etm.2018. 6755. PMID：6257662.
[25] Li XR，Zhou J，Huang K. Inhibition of the lncRNA Mirt1 attenuates acute myocardial infarction by suppressing NF-kappa B activation [J]. Cell Physiol Biochem，2017， 42（3）：1153-1164. doi：10.1159/000478870.