|
|
Clinical effect of small needle knife combined with Modified Shuanghe Decoction in the treatment of knee osteoarthritis with syndrome of blockade of phlegm and blood stasis |
TONG Ying1* SHAO Zhonglin2* ZHANG Weiping2 YANG Junzhao2 HU Rongxue2 TAN Jiahui2 |
1.Department of Rheumatology, the First Affiliated Hospital of Heilongjiang University of Chinese Medicine, Heilongjiang Province, Harbin 150040, China;
2.Graduate School, Heilongjiang University of Chinese Medicine, Heilongjiang Province, Harbin 150040, China |
|
|
Abstract Objective To observe the clinical efficacy of small needle knife combined with Modified Shuanghe Decoction in the treatment of knee osteoarthritis with syndrome of blockade of phlegm and blood stasis. Methods From January 2018 to January 2019, 60 cases of knee osteoarthritis patients with syndrome of blockade of phlegm and blood stasis admitted to Outpatient Department of Rheumatology of the First Affiliated Hospital of Heilongjiang University of Chinese Medicine were selected and randomly divided into needle knife group and Chinese medicine group and needle knife combined with Chinese medicine group by random number table method, with 20 cases in each group. The needle knife group was treated with needle knife release. The Chinese medicine group was treated with Modified Shuanghe Decoction orally. The needle knife combined with Chinese medicine group was treated with Modified Shuanghe Decoction combined with needle knife release. All three groups took 2 months as a course. The knee joint visual analogue scale (VAS) and Lysholm scale before and after treatment and therapeutic effect of Chinese medicine after treatment were observed among the three groups. Results There were no significant differences of VAS score and Lysholm score among the three groups before treatment (P > 0.05). After treatment, the Lysholm score of the needle knife combined with Chinese medicine group was higher than that of the needle knife group and the Chinese medicine group, and the VAS score was lower than that of the needle knife group and the Chinese medicine group, the differences were all statistically significant (P < 0.05). The total effective rate of the needle knife combined with Chinese medicine group was higher than that of the needle knife group and the Chinese medicine group, the differences were statistically significant (P < 0.05), while there was no significant difference of the total effective rate between the needle knife group and the Chinese medicine group (P > 0.05). Conclusion Small needle knife combined with Modified Shuanghe Decoction in the treatment of knee osteoarthritis with syndrome of blockade of phlegm and blood stasis can effectively relieve knee pain, improve knee function, control disease development, and enhance patients′ quality of life, which is worthy of clinical promotion.
|
|
|
|
|
[1] 张金焕,张剑勇.补肾通痹泰颗粒联合麝香海马追风膏外敷治疗膝骨性关节炎的疗效观察[J].广州中医药大学学报,2019,36(4):503-507.
[2] 曹振武,黄永明,田振江,等.针刀联合局部封闭治疗膝骨关节炎临床疗效观察[J].中国中医骨伤科杂志,2018, 26(8):18-20,25.
[3] 余红超,孙菊,董博,等.针刀整体松解术配合蠲痹汤治疗肝肾亏虚型膝骨性关节炎临床观察[J].中国医药导报,2017,14(3):169-172.
[4] 王波,余楠生.膝骨关节炎阶梯治疗专家共识(2018年版)[J].中华关节外科杂志:电子版,2019,13(1):124-130.
[5] 国家食品药品监督管理局.中药新药临床研究指导原则[S].北京:中国医药科技出版社,2002:210.
[6] 吴绪平,张天民.针刀医学临床诊疗与操作规范[S].北京:中国中医药出版社,2012:66-67.
[7] 张静,李炳奇,任杰.针刀松解联合臭氧关节腔注射治疗膝骨关节炎的疗效观察[J].中医正骨,2017,29(5):10-13.
[8] 秦谊,李峰,刘清国,等.针刀松解法治疗膝骨性关节炎的机理[J].中国康复理论与实践,2010,16(4):397-398.
[9] 任树军,任明辉,王墉琦,等.局部封闭配合针刀治疗痰湿阻滞型膝关节滑膜皱襞综合征48例[J].中国中医骨伤科杂志,2016,24(12):38-41.
[10] 刘英民,赵雪竹.针刀治疗膝关节创伤性滑膜炎40例疗效分析[J].海南医学,2015,26(1):109-111.
[11] 陈志军,张大华.丹杞颗粒联合硫酸氨基葡萄糖治疗骨性关节炎的疗效研究[J].中国骨质疏松杂志,2018,24(7):900-903.
[12] 林璐璐,孙宁,王雪蕊,等.膝关节骨性关节炎常用评价量表的比较与分析[J].中国疼痛医学杂志,2018,24(2):135-139.
[13] 田晓美,赵紫砚,侯丽.膝关节骨性关节炎中西医结合康复治疗进展[J].现代中西医结合杂志,2016,25(1):105-108.
[14] 张建林,任睿双.加味益肾强骨汤联合三步推拿点穴手法治疗膝骨性关节炎的临床研究[J].中国中医骨伤科杂志,2018,26(1):34-38.
[15] 刘建民,刘晶.从经筋弓弦特性探析针刀治疗膝骨性关节炎[J].中国医药导报,2017,14(27):161-164.
[16] 张礼平,程飞,刘德玉,等.生物力学在膝骨性关节炎中的应用进展[J].中华中医药学刊,2016,34(7):1644-1647.
[17] 苏兴平,王海东,安维新,等.针刀松解术治疗颈椎病240例临床疗效分析[J].中国中医骨伤科杂志,2019,27(3):53-55.
[18] 佟颖,刁志惠,孙乐,等.小针刀联合二妙丸加减方治疗湿热浸淫型强直性脊柱炎临床疗效观察[J].辽宁中医药大学学报,2018,20(7):8-10.
[19] 杨康栋,李发炘,梁延昌,等.双合汤对膝骨性关节炎大鼠关节液中PGE_2、MDA、SOD及MMP-3的影响[J].动物医学进展,2018,39(7):63-66.
[20] 陈璐,陈崇民.加减双合汤熏洗对半月板部分切除术后膝关节功能恢复影响[J].中医药临床杂志,2017,29(5):706-708. |
|
|
|