慢性心力衰竭中医证型与左室射血分数相关性的Meta分析

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Abstract Objective To systematically evaluate the correlation between TCM syndromes and left ventricular ejection fraction in chronic heart failure. Methods The electronic databases such as CNKI, VIP, Wanfang and PubMed were retrieved by computer, and the references included in the literature were retrieved. Literature data on correlation between TCM syndromes of chronic heart failure and left ventricular ejection fraction were selected. The retrieval time was from the establishment of database to August 2018. Two graduate students independently searched and screened the literature according to the inclusion and exclusion criteria. The quality of the included literature was evaluated according to Newcastle-Ottawa Scale score. Finally, RevMan 5.3 software was used for Meta-analysis. Results A total of 9 articles with 971 patients were enrolled. The baselines included in the literature were comparable. Chronic heart failure with syndrome of water overflowing due to yang deficiency was compared with syndrome of qi deficiency of heart and lung [MD = -11.47, 95%CI (-15.52, -7.42), P < 0.000 01], syndrome of deficiency both qi and yin [MD = -8.75, 95%CI (-10.72, -6.78), P < 0.000 01], syndrome of blood stasis due to qi deficiency [MD =-7.33, 95%CI (-8.07, -6.59), P < 0.000 01] respectively, the difference was statistically significant. The sensitivity analysis was consistent, the funnel plot showed partial publication bias. Conclusion The low left ventricular ejection fraction can be used as one of the reference indicators for the objective diagnosis of chronic heart failure.

Key words： Left ventricular ejection fraction Chronic heart failure Syndrome of qi deficiency of heart and lung Syndrome of deficiency of both qi and yin Syndrome of blood stasis due to qi deficiency Syndrome of water overflowing due to yang deficiency Meta analysis

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	LI Xingxing1* WU Yang2* FAN Zongjing2 CUI Jie2 LIU Qinyao2 LI Zhengyu1 LI Mingxuan1 LI Yan2

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LI Xingxing1* WU Yang2* FAN Zongjing2 CUI Jie2 LIU Qinyao2 LI Zhengyu1 LI Mingxuan1 LI Yan2. Meta-analysis of correlation between TCM syndromes and left ventricular ejection fraction in chronic heart failure[J]. 中国医药导报, 2019, 16(21): 143-146,150.

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http://www.yiyaodaobao.com.cn/EN/ OR http://www.yiyaodaobao.com.cn/EN/Y2019/V16/I21/143

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