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| Clinical effect of proximal fibula osteotomy combined with injection of chitosan into the articular cavity in the treatment of early and middle medial compartment osteoarthritis of knee joint |
| HE Junyuan TANG Jianbang▲ ZHENG Weihong GAO Dawei WU Yufeng |
| The Third Department of Orthopaedics, Zhongshan Hospital of Traditional Chinese Medicine, Guangdong Province, Zhongshan 528400, China |
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Abstract Objective To study the clinical effect of proximal fibula osteotomy combined with injection of chitosan into the articular cavity in the treatment of early and middle medial compartment osteoarthritis of knee joint. Methods The clinical data of 83 patients with early and middle medial compartment knee osteoarthritis admitted to Zhongshan Hospital of Traditional Chinese Medicine in Guangdong Province from January 2016 to December 2017 were retrospectively analyzed. According to the different treatment, the patients were divided into observation group and control group. In the observation group, 42 cases were treated with proximal fibula osteotomy combined with intra-articular chitin injection, while in the control group, 41 cases were treated with proximal fibula osteotomy alone. The changes of preoperative general data, surgical clinical data, visual analogue score (VAS), WOMAC score and American knee association score (AKS) were analyzed and compared. Results There were no statistical significances in the comparison of pain to operation time, operation time, intraoperative blood loss and hospitalization time between the two groups (P ＞ 0.05). Comparison of preoperative VAS, WOMAC and AKS scores between the two groups showed no statistically significant difference (P ＞ 0.05). VAS score and WOMAC score decreased gradually at 1, 3 and 6 months after surgery in the observation group, while AKS knee and knee function score increased gradually, with statistically significant difference from that before surgery (P ＜ 0.05); VAS scores and WOMAC scores at 1, 3 and 6 months after surgery in the observation group were lower than those in the control group, while AKS knee and knee function scores were higher than those in the control group, with statistical ly significant differences (all P ＜ 0.05). Conclusion Proximal fibular osteotomy combined with injection of chitosan into the articular cavity for the treatment of early and middle medial compartment knee osteoarthritis can significantly relieve knee pain, improve knee joint function, and delay the process of knee osteoarthritis.
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