早发性及迟发性急性缺血性卒中后癫痫的临床特点分析

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Abstract Objective To investigate the clinical characteristics of early and late onset epilepsy after acute ischemic stroke. Methods Clinical data of 3108 patients with acute ischemic stroke in the Department of Neurology of Fujian Provincial Hospital from June 2012 to June 2016 was retrospectively analyzed, with long-term follow-up (2-6 years). A total of 108 patients with epilepsy after stroke were divided into early-onset epilepsy group (41 cases) and late-onset epilepsy group (67 cases) depends on the time of attack. The clinical and imaging data, classification of seizures, occurrence rate of epileptic status and eeg results of the two groups were analyzed. Results The proportion of males in the late-onset epilepsy group was higher than that in the early-onset epilepsy group (P ＜ 0.05). The mean age of later-onset epilepsy group was lower than that of early-onset epilepsy group (P ＜ 0.05). The seizure types in the early onset epilepsy group were mainly simple or complex partial seizure, while those in the late onset epilepsy group were mainly partial secondary comprehensive seizure (P ＜ 0.05). Cerebrovascular disease risk factors, National Institutes of health stroke scale score, occurrence rate of epileptic status, abnormal occurrence rate of electroencephalogram, cortical involvement rate, occurrence rate of hemorrhagic cerebral infarction, etc. were compared between the two groups, and the differences were not statistically significant (P ＞ 0.05). Conclusion The patients with delayed epilepsy after acute ischemic stroke are younger and more male. The main attack form of early onset patients is simple or complex partial attacks, and the main attack form of late onset patients is partial secondary comprehensive attacks.

Key words： Stroke Ischemic stroke Epilepsy Epileptic attack

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	FU Mengmeng1 WANG Yinzhou2 LI Yongkun2 CHENG Qiong2 ZHENG Zheng2

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FU Mengmeng1 WANG Yinzhou2 LI Yongkun2 CHENG Qiong2 ZHENG Zheng2. Analysis on the clinical characteristics of early and late onset epilepsy after acute ischemic stroke[J]. 中国医药导报, 2019, 16(20): 84-87.

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http://www.yiyaodaobao.com.cn/EN/ OR http://www.yiyaodaobao.com.cn/EN/Y2019/V16/I20/84

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