慢性心力衰竭与淋巴细胞和细胞因子相关性的研究进展

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Abstract Chronic heart failure (CHF) is a complex clinical symptom group. As the ultimate outcome of most cardiovascular diseases, it is one of the main causes of death of heart disease. The pathogenesis of CHF is complex. In recent years, with the deepening of research, it has been found that immune factors play an important role in the disease process. B lymphocyte and T lymphocyte damage myocardium through different ways of action, induce and aggravate pathological ventricular remodeling, and ultimately accelerate the occurrence and development of CHF. Tumor necrosis factor-α and interleukin-6, as the representatives of proinflammatory cytokines, can accelerate the development of CHF. Cytokines such as IL-33 can protect the heart and delay the progression of CHF. This article reviews the recent research progress of lymphocytes and cytokines related to the occurrence and development of CHF in order to provide new ideas for its clinical treatment in the future.

Key words： Chronic heart failure Lymphocyte Cytokines Interleukin Ventricular remodeling

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	Articles by authors
	XU Xiaowen1
	2 LI Yiping1
	2 RUAN Xiaofen1
	2 WANG Xiaolong1
	2

Cite this article:

XU Xiaowen1,2 LI Yiping1,2 RUAN Xiaofen1, et al. Research progress on the relationship between chronic heart failure and lymphocytes and cytokines[J]. 中国医药导报, 2019, 16(20): 41-44.

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http://www.yiyaodaobao.com.cn/EN/ OR http://www.yiyaodaobao.com.cn/EN/Y2019/V16/I20/41

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