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| Clinical study of Yangyin Xifeng Fumai Decoction in the treatment of premature ventricular contraction with syndrome of insufficiency of heart Yin and wind-driven heart collaterals |
| ZHANG Limei1 HU Yuanhui1 CHEN Jin2 |
1.Department of Cardiology, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100053, China;
2.Clinical Medical College, Beijing University of Chinese Medicine, Beijing 100029, China |
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Abstract Objective To observe the curative effect of Yangyin Xifeng Fumai Decoction on premature ventricular contraction with the syndrome of insufficiency of heart Yin and wind-driven heart collaterals. Methods The patients with premature ventricular contraction who were diagnosed as insufficiency of heart Yin and wind-driven heart collaterals syndrome admitted to Guang'anmen Hospital, China Academy of Chinese Medical Sciences and its south area from November 2011 to August 2016 were randomly divided into treatment group and control group by random number table method, with 70 cases in each group. The treatment group was given Yangyin Xifeng Fumai Decoction, while the control group received the treatment of Metoprolol. The course of both groups were (28±2) days. The differences of clinical curative effect, the curative effect of 24 hours dynamic electrocardiogram and the heart rate variability (HRV) between two groups were compared. Results At the end of treatment, 1 case of treatment group and 2 cases of control group were lost. The total effective rate of Chinese medicine syndrome was 89.9% in the treatment group, 72.1% in the control group, the treatment group was superior to the control group (P ＜ 0.05); the total effective rate of 24 hours dynamic electrocardiogram was 73.9% in the treatment group, 67.6% in the control group, the difference between the two groups was not statistically significant (P ＞ 0.05). After treatment, both groups were significantly higher than before treatment in SDNN, SDANN, PNN50, RMSSD indexes (P ＜ 0.05), and the treatment group was significantly better than the control group in SDNN, SDANN and RMSSD indexes (P ＜ 0.05). Conclusion Yangyin Xifeng Fumai Decoction can effectively improve the symptom, the number of premature ventricular contraction and the HRV in patients with premature ventricular contraction diagnosed as insufficiency of heart Yin and wind-driven heart collaterals syndrome, the security is good.
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