补肾疏肝方治疗肾虚肝郁型复发性流产的临床效果

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Abstract Objective To explore the clinical effect of Bushen Shugan Prescription in the treatment of recurrent spontaneous abortion with syndrome of kidney deficiency and liver depression. Methods The recurrent spontaneous abortion patients with syndrome of kidney deficiency and liver depression in Traditional Chinese Medicine Hospital of Wenzhou City from July 2015 to November 2016 were selected as research objects, and they were randomly divided into control group and treatment group. The control group received Progesterone Injection alone, the treatment group received Progesterone Injection combined with traditional Chinese medicine. The clinical comprehensive therapeutic effect, TCM symptom score, the max diameter line of gestational sac, self-rating anxiety scale (SAS), and the levels of serum human chorionic gonadotropin (β-HCG), progesterone in the two groups were observed. Results The total effective rate in the treatment group was 88.0%, which was significantly higher than that of control group (72.0%), there was statistically significant difference (P ＜ 0.05). TCM syndrome score of treatment group after treatment was lower than that before treatment and that of control group after treatment, the differences were statistically significant (P ＜ 0.05). After treatment, the max diameter line of gestational sac of the two groups was both higher than those before treatment, and the max diameter line of gestational sac in the treatment group after treatment was higher than that of control group, the differences were statistically significant (P ＜ 0.05). After treatment, the SAS score of treatment group was lower than that before treatment, the SAS score of control group was higher than that before treatment, the differences were statistically significant (P ＜ 0.05), the SAS score of treatment group after treatment was lower than that of control group, the difference was statistically significant (P ＜ 0.05). After pregnancy for 5, 6 weeks, the levels of serum progesterone in the treatment group were lower than those of control group, the levels of β-HCG were higher than those of control group, the differences were statistically significant (P ＜ 0.05), while there were no statistically significant differences of serum progesterone, β-HCG between the two groups after pregnancy for 8, 10 weeks (P ＞ 0.05). Conclusion Bushen Shugan Prescription can increase the success rate of preventing miscarriages of recurrent spontaneous abortion patients with syndrome of kidney deficiency and liver depression, improve anxiety state, which is safe and effective in clinic.

Key words： Recurrent spontaneous abortion Syndrome of kidney deficiency and liver depression Bushen Shugan Prescription

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	QIAN Yanqing MA Dazheng SUN Yun

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QIAN Yanqing MA Dazheng SUN Yun. Clinical effect of Bushen Shugan Prescription in the treatment of recurrent spontaneous abortion with syndrome of kidney deficiency and liver depression[J]. 中国医药导报, 2017, 14(16): 86-89.

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http://www.yiyaodaobao.com.cn/EN/ OR http://www.yiyaodaobao.com.cn/EN/Y2017/V14/I16/86

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