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Characteristic and drug choice of Urology surgical postoperative infection |
LI Lixia1 LI Yongyang2▲ |
1.Department of Pharmaceutical, Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai 200092, China;
2.Department of General surgery, East Campus of Sixth People's Hospital Affiliated to Shanghai Jiaotong University, Shanghai 201306, China |
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Abstract Objective To analyze the characteristics and trends of urology surgical postoperative infection, in order to provide references for clinical pharmacists. Methods From January 2010 to December 2015, in Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine, 228 urology surgical postoperative infection patients with clinical pharmacists were consulted were analyzed retrospectively. According to these diseases categories, they were divided into four groups, kidney stone group (n = 90), ureteral calculus group (n = 35), kidney and ureteral calculus group (n = 21) and other disease group (n = 82). The infection sites, bacterial categories, anti-infection treatment schedules, and treatment outcome were analyzed individually. Results The infection sites were mainly urinary tract, blood system or lungs. Except for the blood system infection, the difference of incidence rate of the other infection sites among the four groups was statistically significant (P < 0.01). E. coli had the highest detection rate, and the difference of its infection rate among four groups was statistically significant (P < 0.01). Candida albicans had the second highest infection rate, and Enterococcus had the third highest infection rate. Imipenem had the highest usage rate, and Piperacillin-Tazobactam had the second highest usage rate. 47% patients were cured, 50.9% patients were improved. the difference of recovery rate among the four groups was statistically significant (P < 0.05). Conclusion Clinical pharmacists analyze the common infection sites, pathogens and effective anti-infection treatment schedules, and take an active role in curing infection and reducing infection mortality rate.
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