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| Analysis of surgical complications of huge meningiomas |
| WANG Rui SUN Hongwei WANG Chao ZHANG Rende LI Dongming |
| Department of Neurosurgery, First Affiliated Hospital of Zhengzhou University, He'nan Province, Zhengzhou 450052, China |
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Abstract Objective To study the influencing factors and harm of the surgical complications of huge meningiomas, and summarize the experience for huge meningiomas prevention and treatment. Methods The clinical data of 64 patients with huge meningioma were analyzed retrospectively from September 2011 to September 2016 in the First Affiliated Hospital of Zhengzhou University. The quality of life was assessed by KPS score. Single factor chi-square test and multiple factor Logistic regression for statistics data,and then combined with clinical and related literature to summarize the causes of surgical complications, influencing factors, preventive measures and outcome. Results Univariate analysis showed that age, preoperative KPS score, tumor location and degree of resection were related to the surgical complications (P < 0.05). Multivariate analysis showed that age was ≥60 years old and incomplete resection were independent risk factors for complications. Severe cerebral edema and intracranial hemorrhage are independent risk factors for perioperative outcome (P < 0.05). Conclusion Severe cerebral edema and intracranial hemorrhage are serious complications of huge meningioma. The patients are older and the tumor is incomplete resection were Independent risk factors for surgical complications. Scientific and fine surgical operation and reasonable perioperative management can be reduced the risk of surgical complications.
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