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| Changes and significance of myocardial enzyme in the patients with acute cerebrovascular disease |
| REN Yongxia |
| Department of Clinical Laboratory, Yi′nan People′s Hospital of Linyi City, Shandong Province, Yi′nan 276300, China |
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Abstract Objective To investigate the changes and significance of myocardial enzyme in the patients with acute cere?鄄brovascular disease. Methods The clinical data of 68 patients with acute cerebrovascular disease (acute cerebrova?鄄scular disease group) admitted to People′s Hospital of Linyi City ("our hospital" for short) from August 2015 to December 2016 was analyzed retrospectively, 55 cases of healthy control in our hospital at the same time were selected as normal control group. The levels of aspartate aminotransferase (AST), lactic dehydrogenase (LDH), α-hydroxybutyrate dehydrogenase (α-HBDH), creatine kinas (CK), creatine Kinase Isoenzyme (CK-MB) were detected, and electrocardio?鄄gram was examined. Results The levels of AST, LDH, α-HBDH, CK in the acute cerebrovascular disease group were all higher than those of acute cerebrovascular disease group, the differences were all statistically significant (P < 0.05). There were no statistically significant differences of all indexes of myocardial enzyme between cerebral infarction group and cerebral ischemia group (P > 0.05). According to China stroke scale, the levels of CK in the medium group were signi?鄄ficantly higher than those of light group (P ＜ 0.05), the levels of all indexes of myocardial enzyme in the severe group were all higher than those of light group, the differences were all statistically significant (P ＜ 0.05). The levels of all indexes of myocardial enzyme in the non-conscious disturbance group were all lower than those of conscious disturbance group, the differences were all statistically significant (P ＜ 0.05). There were no statistically significant differences of all indexes of myocardial enzyme between normal electrocardiogram group and abnormal electrocardiogram group (P > 0.05). Conclusion Acute cerebrovascular disease can damage cardiac function, cause the changes of myocardial enzyme, which may be related to the severity of illness, conscious disturbance or not. Myocardial enzyme can be considered as the indexes of judging the severity degree of illness and prognosis of patients with acute cerebrovascular disease.
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