蛛网膜下腔出血患者头痛发作时经颅多普勒超声监测指标变化的临床研究

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Abstract Objective To identify the etiology of headache in patients with subarachnoid hemorrhage, in order to provide timely and effective treatment guidelines for patients. Methods The clinical data of 61 patients with subarachnoid hemorrhage treated in Neurology Department of CNPC Central Hospital from May 2010 to December 2013 were analyzed retrospectively. TCD was used to monitor the changes of MCA, PCA and BA blood flow velocity in patients with subarachnoid hemorrhage during hospitalization and headache attack. According to the results of TCD, patients were divided into two groups. Patients in group A were corresponded to cerebral vasospasm, patients in group B were not corresponded to cerebral vasospasm. The TCD indexes and treatment effect of the two groups were compared. Results There were 78 case-times (53.8%) in group A. The MCA, PCA and BA blood flow velocity of patients at headache attack were increased than at hospitalization in group A, the differences were statistically significant (P ＜ 0.05), and it was considered to be caused by cerebral vasospasm. All patients had remission after given timely and effective treatment. There were 67 case-times (46.2%) in group B. The differences of MCA, PCA and BA blood flow velocity between patients at hospitalization and headache attack in group B had no statistically significant (P > 0.05), and it was unrelated to cerebral vasospasm. 50 case-times (75%) of patients had remission after given alleviate cerebral edema treatment. Conclusion The changes of TCD monitoring data of SAH patients provide reliable evidences for cerebral vasopasm diagnosis. TCD real-time monitoring has important clinical value for finding and identifying cerebral vasopasm and cerebral edmema.

Key words： Subarachnoid hemorrhage Cerebral vasospasm Brain edema Transcranial Doppler Nim Mannitol

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KANG Zhixin. A clinical study on changes of transcranial Doppler in patients with subarachnoid hemorrhage during headache attack[J]. 中国医药导报, 2017, 14(20): 94-96,112.

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http://www.yiyaodaobao.com.cn/EN/ OR http://www.yiyaodaobao.com.cn/EN/Y2017/V14/I20/94

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