超声心动图在慢性肾脏病患者心血管疾病筛查中的应用价值

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Abstract Objective To investigate the value of echocardiography in screening of cardiovascular disease in patients with chronic kidney disease (CKD). Methods From September 2013 to July 2016, in Shunyi Hospital of Beijing Chinese Medicine Hospital ("our hospital" for short), 78 CKD patients were selected as the CKD group, and 78 healthy volunteers in our hospital were selected as the control group at the same period, the general survey data, echocardiography imaging and renal function index were recorded and given correlation analysis. Results There were no statistically significant differences in gender, age, systolic blood pressure, diastolic blood pressure, body mass index between the two groups (P > 0.05). The LAD, LVDd, LVDs, LVESV, LVEDV, E/A in the CKD group were (37.11±2.19) cm, (5.11±0.44) cm, (3.69±0.83) cm, (49.20±11.49) mL, (108.33±22.19) mL and (1.02±0.32), thoes in the control group were (34.11±3.10) cm, (4.72±0.44) cm, (2.93±0.44) cm, (25.02±5.66) mL and (76.20±13.10) mL and (1.27±0.44), there were statistically significant differences between the two groups in this index (P < 0.05). The Cr and BUN values of the CKD group were significantly higher than those of the control group, the differences were statistically significant (P < 0.05). There were no significant differences in UA, Hb, TG and LDL-C between the two groups (P > 0.05). In the CKD group, Pearson coefficient correlation analysis showed that LAD, LVDd, LVDs, LVESV, LVEDV were significantly positively correlated with Cr (r = 0.334, 0.514, 0.442, 0.298, 0.332, P < 0.05), E/A was negatively correlated with Cr (r = -0.345, P < 0.05), LAD, LVDd were positively correlation to BUN(r = 0.442, 0.301, P < 0.05). Multivariate regression analysis showed that LAD, LVDd, LVDs, E/A were the main independent risk factors for Cr (P < 0.05), LAD and LVDd were the main independent risk factors for BUN (P < 0.05). Conclusion The application of echocardiography in the screening of cardiovascular disease in patients with chronic kidney disease can effectively reflect the state of the heart function and the condition of the patients, and it is closely related to the routine indexes of renal function.

Key words： Echocardiography Chronic kidney disease Cardiovascular disease Correlation

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	DONG Xin1 LI Renwu2 JI Limei2

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DONG Xin1 LI Renwu2 JI Limei2. Application value of echocardiography in screening of cardiovascular disease in patients with chronic kidney disease[J]. 中国医药导报, 2017, 14(28): 121-124,132.

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http://www.yiyaodaobao.com.cn/EN/ OR http://www.yiyaodaobao.com.cn/EN/Y2017/V14/I28/121

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