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| Comparison of efficacy of oral Vitamin D in the treatment of vitamin D deficiency in infants of Han nationality and Uygur nationality |
| ZHU Ranke1 YAN Huiheng2 LIU Ying2 WU Jieling1▲ |
1.Department of Child Health, Guangdong Maternal and Child Health Hospital, Guangdong Province, Guangzhou 510010, China;
2.Department of Neonatology, Guangdong Maternal and Child Health Hospital, Guangdong Province, Guangzhou 510010, China |
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Abstract Objective To study the difference between Han and Uygur children with vitamin D deficiency after the same treatment. Methods One hundred Han children and 100 Uygur children who were diagnosed with vitamin D deficiency and treated in Kashi Maternal and Child Health Care Hospital from May 2015 to December 2016 were recruited and divided into Han nationality group and Uygur nationality group. The serum 25OHD values of each child were recorded at the beginning. There were no significant differences in age, sex and initial 25OHD level between the two groups (P ＞ 0.05). The treatment plan was to take 800 U Vitamin D3 daily. The serum 25OHD level was reexamined every three months. The treatment would stop while one′s serum 25OHD level was more than 75 nmol/L. The variation of serum 25OHD levels between the two groups during the same cycle were compared. Results The serum 25OHD of the children in the Han nationality group and Uygur nationality group increased significantly at each review every three months compared with the serum 25OHD values at the beginning (P ＜ 0.05). The serum 25OHD of the children in Han nationality group was significantly higher than that of the children in Uygur nationality group at each review (P ＜ 0.05). After the same treatment time, the variation of serum 25OHD in Han nationality group was significantly bigger than that in Uygur nationality group (P ＜ 0.05). Conclusion This treatment plan has a good curative effect on Han and Uygur children, and can effectively improve the serum 25OHD level in children with vitamin D deficiency. However, the effect of this plan on Uygur children is worse than that on Han children. It should be considered to increase the daily supplementary dose of Vitamin D in Uygur children.
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