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Research progress of thymectomy in the treatment of non-thymomatous myasthenia gravis |
LI Jinpin XU Hongyan MO Xuean▲ |
Department of Neurology, the First Affiliated Hospital of Guangxi Medical University, Guangxi Zhuang Autonomous Region, Nanning 530021, China |
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Abstract Myasthenia gravis (MG) is an autoimmune disease involving neuromuscular junction, taking pathological fatigue of skeletal muscle as main characteristics, its pathogenesis is closely related to thymic lesion, such as thymoma, megalothymus, lymphoblastic follicular hyperplasia, and thymic atrophy. The treatment of MG includes application of cholinesterase inhibitors, immunosuppressor, immune globulin, plasmapheresis and thymectomy, the effect of thymectomy in the treatment of MG patients combined with thymoma is exact. In recent years, some scholars have reported that thymotomy can be used to treat MG patients with non-thymoma, but its therapeutic value is controversial at present. This paper reviews the research progress of thymectomy in the treatment of non-thymomatous MG.
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