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Research progress of gastrointestinal flora and tumor chemotherapy drugs |
TIAN Cheng1 YUAN Anlong2 |
1.School of Medicine, Wuhan University of Science and Technology, Hubei Province, Wuhan 430065, China;
2.Department of Gastroenterology, Xiaogan Hospital Affiliated to Wuhan University of Science and Technology, Hubei Province, Xiaogan 432000, China |
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Abstract The microbiome consists of symbiotic bacteria and other microorganisms present in host epithelial barriers. Microflora plays an important role in maintaining local homeostasis and systematically regulating physiological functions such as metabolism, hematopoiesis, inflammation and immunity. Microbiota are also involved in the occurrence, development and spread of cancer in epithelial barriers and sterile tissues. Gastrointestinal microbes are involved not only in cancer, but also in cancer prevention and chemotherapy. This article reviews the relationship between gastrointestinal microecology and tumor and chemotherapy.
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