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Clinical efficacy of traditional Chinese medicine combined with rectal ultrasound phoresis in the treatment of chronic non-bacterial prostatitis |
WANG Peng WU Shaoqin HUANG Jie LONG Xiangqian LU Dandan |
Department of Surgery, Jiangning TCM Hospital, Jiangsu Province, Nanjing 211100, China |
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Abstract Objective To explore clinical efficacy of traditional Chinese medicine combined with rectal ultrasound phoresis in the treatment of chronic non-bacterial prostatitis. Methods From July 2013 to September 2014, 138 patients with chronic non-bacterial prostatitis in Jiangning TCM Hospital were divided into control group and observation group by random number table, with 69 cases in each group. The control group was treated with compound Chinese medicine blood stasis Sanjie blood activating agent, while the observation group was treated with traditional Chinese medicine combined with rectal ultrasound phoresis. Total efficiency, chronic prostatitis symptom (NIH-CPSI) score, TCM syndromes, urinary flow rate (UFR), residual urine volume (RVU), white blood cell count, interleukin-8 (IL-8) and tumor necrosis factor α (TNF-α) of patients in two groups were compared. Results ①Total efficiency in observation group after treatment was significantly higher than control group (P < 0.05). ②NIH-CPSI score and TCM syndromes scores in observation group after treatment were significantly lower than before treatment and control group (P < 0.05). ③MFR in observation group after treatment was significantly higher than before treatment and control group (P < 0.05). RVU and EPS-WBC in observation group after treatment were significantly lower than before treatment and control group (P < 0.05). ④The levels of IL-8 and TNF-α in observation group after treatment were significantly lower than before treatment (P < 0.05). And the level of IL-8 in observation group after treatment was significantly lower than control group (P < 0.05). Conclusion Traditional Chinese medicine combined with rectal ultrasound phoresis can improve clinical outcomes in patients with chronic non-bacterial prostatitis, reduce pain and voiding symptoms, improve quality of life for chronic nonbacterial prostatitis patients.
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[1] 魏锐,李兰群,戴继灿,等.丹益片治疗慢性前列腺炎安全性及有效性的随机、双盲双模拟、阳性药平行对照、多中心临床研究[J].中国男科学杂志,2015,20(5):21-25.
[2] Zhang R,Sutcliffe S,Giovannucci E,et al. Lifestyle and risk of chronic prostatitis/chronic pelvic pain syndrome in a cohort of united states male health professionals [J]. J Urol,2015,194(5):1295-1300.
[3] 王高能,童宪楼,朱彦,等.雷公藤多甙联合经直肠超声理疗治疗难治性IIIB型前列腺炎的临床观察[J].中国男科学杂志,2013,24(9):54-55.
[4] Schaeffer EM. Re:effectiveness of acupuncture on chronic prostatitis-chronic pelvic pain syndrome category ⅢB patients:a prospective,randomized,nonblinded,clinical trial [J]. J Urol,2015,194(4):1007-1008.
[5] Kobayashi I,Ikawa K,Nakamura K,et al. Penetration of piperacillin- tazobactam into human prostate tissue and dosing considerations for prostatitis based on site-specific pharmacokinetics and pharmacodynamics [J]. J Infect Che?鄄mother,2015,21(8):575-580.
[6] 陈望强,俞佳,丁彩飞,等.鲍氏前列灌肠方配合前列回春胶囊治疗慢性非细菌性前列腺炎的疗效观察[J].中华全科医学,2017,15(2):325-327.
[7] 宫满成,董文静,丘少鹏,等.超声电导靶向导入头孢菌素治疗慢性前列腺炎80例的临床分析[J].现代生物医学进展,2016,16(5):864-867.
[8] 郑筱萸.中药新药临床研究指导原则[M].北京:中国医药科技出版社,2002.
[9] 琚保军.袪瘀通闭汤规范保留灌肠对慢性前列腺炎患者炎症介质及血流变的干预[J].世界科学技术:中医药现代化,2015,30(6):1215-1219.
[10] 徐红亮.盐酸坦索罗辛胶囊在慢性非细菌性前列腺炎中的应用[J].中国医药导报,2015,12(6):99-102.
[11] 刘敏,朱同玉,颜伟,等.地奥斯明对老年慢性前列腺炎患者血清及前列腺液内免疫介导因子的影响及临床疗效研究[J].中国生化药物杂志,2015,20(6):121-123.
[12] Sah VK,Wang L,Min X,et al. Multiparametric MR imaging in diagnosis of chronic prostatitis and its differentiation from prostate cancer [J]. Radiol Infect Dis,2015,1(2):70-77.
[13] 李小莉,蓝献全,潘素珍,等.复方前列安颗粒治疗慢性无菌性前列腺炎大鼠的药效学研究[J].中国临床药理学杂志,2015,31(6):1656-1658.
[14] Kü?觭ük EV,Su?觭eken FY,Binday?覦 A,et al. Effectiveness of acupuncture on chronic prostatitis-chronic pelvic pain syndrome category ⅢB patients:a prospective,randomized,nonblinded,clinical trial [J]. Urology,2015,85(3):636-640.
[15] 刘清尧,韩亮,张新荣,等.穴位电刺激联合栓剂治疗Ⅲ型前列腺炎气滞血瘀型38例[J].环球中医药,2015,8(8):992-995.
[16] 卢凤迎,廖新红,李智贤,等.微血管密度在经直肠超声血流动力学检测鉴别诊断前列腺癌和慢性前列腺炎中的应用及其评价[J].吉林大学学报:医学版,2014,15(5):1104-1108.
[17] Kutch JJ, Yani MS,Asavasopon S,et al. Altered resting state neuromotor connectivity in men with chronic prostatitis/chronic pelvic pain syndrome:A MAPP:research network neuroimaging study [J]. NeuroImage Clin,2015, 31(5):493-502.
[18] Lee SW,Liong ML,Yuen KH,et al. Acupuncture and immune function in chronic prostatitis/chronic pelvic pain syndrome:a randomized,controlled study [J]. Complement Ther Med,2014,22(6):965-969.
[19] 孙晓慧,张玉刚,曲辑.萆薢、石菖蒲药对治疗慢性非细菌性前列腺炎最佳配伍比例的药效学研究[J].长春中医药大学学报,2017,33(1):16-18.
[20] 吴跃鹏.中药保留灌肠结合直肠微波治疗慢性前列腺炎65例临床观察[J].实用中医内科杂志,2015,14(9):47-49.
[21] 梁凯,贾瑞鹏,苏江浩,等.超声电导靶向治疗难治性慢性非细菌性前列腺炎疗效观察[J].河北医药,2013,35(5):667-668. |
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