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| Effect of Bushen Tongbi Decoction on lumbar disc herniation and its influence on inflammatory factors |
| ZHANG Qiuyuan LI Qing ZHANG Yifan |
| Department of Integrated Traditional Chinese and Western Medicine, the First Hospital of Shijiazhuang, Hebei Province, Shijiazhuang 050011, China |
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Abstract Objective To study the effect of Bushen Tongbi Decoction on lumbar disc herniation (LDH) and its influence on inflammatory factors. Methods From January 2017 to September 2018, 80 LDH patients treated in the First Hospital of Shijiazhuang were studied. According to random number table method, patients were randomly divided into observation group and control group, there were 40 cases in each group. The control group was treated with traction and physiotherapy, the observation group was treated with Bushen Tongbi Decoction on the basis of control group, both groups were treated for 3 weeks. The efficacy, functional and pain score, inflammatory factor, and incidence of adverse reaction before treatment and 3 weeks after treatment was compared between the two groups. Results The total effective rate of the observation group was higher than the control group (P ＜ 0.05). After treatment, the visual analogue scale (VAS) and osuesery dability index (ODI) score in the two groups was lower than before treatment, and the observation group was lower than the control group, the Japanese Orthpaedic assoiationscores (JOA) score was higher than before treatment, and the observation group was higher than that of the control group (P ＜ 0.05). The C-reactive protein, interleukin-1β, tumor necrosis factor-α and IL-6 were lower in the two groups after treatment than before treatment (P ＜ 0.05), and lower in the observation group than in the control group (P ＜ 0.05). The incidence of adverse drug reactions in the observation group was not significantly different compared with that in the control group (P ＞ 0.05). Conclusion The efficacy and safety of Bushen Tongbi Decoction in the treatment of LDH is good. It can also effectively improve the function, pain score and inflammatory state of the patients.
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