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| The study of corneal biomechanics of the Mongols in Inner Mongolia region with rheumatoid arthritis and non-rheumatoid arthritis dry eyes |
| SUN Yaru ZHAO Haixia |
| Myopia Treatment Center, Affiliated Hospital of Inner Mongolia Medical University, Inner Mongolia Autonomous Region, Huhhot 010050, China |
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Abstract Objective To investigate the corneal biomechanics of the Mongols in Inner Mongolia with rheumatoid arthritis （RA） and non-RA dry eyes by Corneal Visualization Scheimpflug Technology （Corvis ST）. Methods The Mongols in Inner Mongolia Region （all Mongols within three generations） were recruited at the Affiliated Hospital of Inner Mongolia Medical University between December 2015 and May 2018. They were divided into non-RA group （92 cases） and RA group （96 cases）. The two groups respectively were performed Corvis ST to detect corneal biomechanics and Corvis ST inspection includes First Applanation Time （A1-time）， Second Applanation Time （A2-time）， First Applanation Length （A1-length）， Second Applanation Length （A2-length）， First Applanation Velocity （A1-V）， Second Applanation Velocity （A2-V）， Highest Concavity Time （HC-time）， Maximum Deformation Amplitude （DA）， Maximum Highest Concavity Radius （HC-radius）， Intraocular Pressure （IOP）， Corneal Center Thickness （CCT）. The differences of the above parameters between the two groups were examined. Results The differences in age， gender， IOP and CCT were not significant between the two groups （P ＞ 0.05）. The Mongols in the RA group had significantly lower A1-time and HC-time， but higher DA compared with the non-RA group （P = 0.01， 0.01， 0.03）. Conclusion There are significent differences in corneal biomechanical properties between RA group and non-RA group of the Mongols. The RA group has a significantly shorter A1-time and HC-time， but larger DA compared with the non-RA group.
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[1] 中华医学会眼科学分会角膜病学组.干眼临床诊疗专家共识（2013 年）[J].中华眼科杂志，2013，49（1）：73-75.
[2] 邹留河.充分认识风湿相关性疾病的眼表病变[J].眼科，2006，15（3）：159-160.
[3] Ausayakhun S，Louthrenoo W，Aupapeng S. Ocular diseases in patients with rheumatic diseases [J]. J Med Assoc Thai，2002，85（8）：855-862.
[4] Moss SE，Klein R，Klein BE. Incidence of dry eye in an older population [J]. Arch Ophthalmol，2004，122（3）：369-373.
[5] Schaumberg DA，Sullivan DA，Buring JE，et al. Prevalence of dry eye syndrome among US women [J]. Am J Ophthalmol，2003，136（2）：318-326.
[6] Hon Y，Lam AK. Corneal deformation measurement using scheimpflug noncontact tonometry [J]. Optom Vis Sci，2013， 90（1）：e1-e8.
[7] Pi?觡ero DP，Alcón N. Corneal biomechanics：a review [J]. Clin Exp Optom，2015，98（2）：107-116.
[8] Perez-Rico C，Guti′errez-Ort′?覦z C，Gonz′alez-Mesa A，et al. Effect of diabetes mellitus on Corvis ST measurement process [J]. Acta Ophthalmol，2015，93（3）：e193-e198.
[9] Hassan Z，Jr ML，Szalai E，et al. Examination of ocular biomechanics with a new Scheimpflug technology after corneal refractive surgery [J]. Cont Lens Anterior Eye，2014， 37（5）：337-341.
[10] Beheshtnejad AH，Hashemian H，Kermanshahani AM，et al. Evaluation of tear osmolarity changes after photorefractive keratectomy [J]. Cornea，2015，34（12）：1541-1544.
[11] Arnett FC，Edworthy SM，Block DA，et al. American Rheumatism Assotiation 1987 revised criteria for the classification of rheumatoid arthritis [J]. Arthritis Rheum，1988，31（3）：315-314.
[12] 汪倩，王琳琳，张妍，等.角膜生物力学特性的测量方法研究现状[J].国际眼科杂志，2016，16（10）：1840-1846.
[13] Valbon BF，Ambr′osio R，Fontes BM，et al. Effects of age on corneal deformation by non-contact tonometry integrated with an ultra-high-speed（UHS）scheimpflug camera [J]. Arq Bras Oftalmol，2013，6（4）：229-232.
[14] Lopes BT，Ramos IC，Dawson DG，et al. Detection of ectatic corneal diseases based on pentacam [J]. Z Med Phys，2016，2（15）：146-147.
[15] Van Doren SR. Matrix metalloproteinase interactions with collagen and elastin [J]. Matrix Biol，2015，44（46）：224-231.
[16] Meyer LM，Kronschl?覿ger M，Wegener AR. Schleimpflug photography detects alterations in corneal density and thickness in patients with dry eye disease [J]. Der Ophthalmologe，2014，111（10）：914-919.
[17] Garcia-Porta N，Fernandes P，Queiros A，et al. Corneal biomechanical properties in different ocular conditions and new measurement techniques [J]. ISRN Ophthalmol，2014，2014：724546.
[18] Pedersen IB，Bak-Nielsen S，Vestergaard AH，et al. Corneal biomechanical properties after LASIK，ReLEx flex，and ReLEx smile by Scheimpflug-based dynamictonometry [J]. Graefes Arch Clin Exp Ophthalmol，2014，252（8）：1329-1335.
[19] 韩晓彤.亚临床期圆锥角膜生物力学变化的相关研究[D].呼和浩特：内蒙古医科大学，2016.
[20] 田磊，吴莹，黄一飞.可视化角膜生物力学分析仪评估青光眼患者角膜生物力学特征[J].眼科，2016，25（1）：30-35. |
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