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Clinical effect of complex trabeculectomy on glaucoma patients with thin Tenon's capsule |
MA Yinghui YANG Jie FU Xiaoxiao DONG Weili |
Department of Ophthalmology, Affiliated Hospital of Chengde Medical College, Hebei Province, Chengde 067000, China |
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Abstract Objective To explore the effect of complex trabeculectomy for glaucoma patients with thin Tenon's capsule. Methods 63 primary glaucoma patients (63 eyes) with thin Tenon's capsule treated in Affiliated Hospital of Chengde Medical College from August 2014 to August 2016 were enrolled retrospectively in the study. All patients accepted trabeculectomy with intraoperative appropriate application of Mitomycin. All patients were observed closely after surgery and accepted early needle suture cut if necessary. The early postoperative anterior chamber formation, filtering bleb and intraocular pressure were observed. The long-term effect of 6 months of follow-up was observed. Results Postoperative 1 month, 60 cases (95.24%) were successful, including 31 cases (93.94%) with Mitomycin, 29 cases (96.67%) without Mitomycin, the difference was not statistically significant (P > 0.05). Type Ⅰ filtering blebs were observed in 7 cases (21.21%) with Mitomycin, and 1 case (3.33%) without Mitomycin, the difference was statistically significant (P < 0.05). Postoperative 6 months, 52 cases (82.54%) were successful, including 30 cases (90.91%) with Mitomycin, 22 cases (73.33%) without Mitomycin, the difference was statistically significant (P < 0.05). Type Ⅰ filtering blebs were observed in 10 cases (30.3%) with Mitomycin, and 2 case (6.67%) without Mitomycin, the difference was statistically significant (P < 0.05). The mean intraocular pressure at 1 week, 1 month and 6 months after operation was (12.63±2.29), (13.69±2.43), (15.33±1.88) mmHg, respectively, those were significantly decreased than that before operation, the differences were statistically significant (P < 0.05). Conclusion Complex trabeculectomy is effective for primary glaucoma with thin Tenon's capsule, early needle suture cut after operation for primary glaucoma with thin Tenon's capsule is simple and effective. It is worthy of promotion and application in primary hospitals.
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[1] 中华医学会眼科学分会青光眼学组.我国原发性青光眼诊断和治疗专家共识(2014年)[J].中华眼科杂志,2014, 50(5):382-383.
[2] 钱韶红.青光眼滤过性手术后浅前房的原因识别及相关处理[J].中国眼耳鼻喉科杂志,2016,16(3):156-159.
[3] 李绍珍.眼科手术学[M].5版.北京:人民卫生出版社,2005:466.
[4] 荣世松,孟海林,梁远波,等.小梁切除术后滤过量的早期物理干预[J].中华全科医师杂志,2012,11(3):208-210.
[5] 宋航,陈康.个性化的青光眼小梁滤过手术疗效观察[J].西南国防医药,2012,22(7):757-759.
[6] Sihota R,Gupta V,Agarwal HC. Long-term evaluation of Trabeculectomy in primary open angle glaucoma and chronic primary angle closure glaucoma in an Asian population[J].Clin Experiment Ophthalmol,2004,32(1):23-28.
[7] Quigley HA,Broman AT. The number of people with glaucoma worldwide in 2010 and 2020 [J]. Br J Ophthalmol,2006,90(3):262-267.
[8] 李璐希,刘伟,季建.小梁切除手术对眼表的影响[J].中华眼科杂志,2013,49(2):185-188.
[9] 李秋明,郑广瑛.眼科应用解剖学[M].郑州:郑州大学出版社,2002:279-281.
[10] 刘辉,肖静,刘蕊.小梁切除术中应用可调节缝线对术后眼压影响观察[J].中国实用眼科杂志,2016,34(9):962-964.
[11] 胡佩宏,刘新华,裴重刚,等.改良的扇形巩膜瓣半隧道切口行复合小梁切除术治疗原发性闭角型青光眼的临床疗效[J].眼科新进展,2016,36(8):738-741.
[12] 刘兴红.无缝线巩膜瓣小梁切除术治疗原发性开角型青光眼的效果[J].中国医药导报,2015,12(21):102-105.
[13] 汤晓东.复合式与传统小梁切除术治疗青光眼疗效的比较[J].医学综述,2014,20(17):3260-3262.
[14] 黄信.复合式小梁切除术治疗青光眼患者的临床研究[J].中国医药导报,2012,9(4):28-29.
[15] Errico D,Scrimieri F,Riccardi R,et al. Trabeculectomy with double low dose of mitomycin C-two years Of follow-up [J]. Clin Ophthalmol,2011,5(12):1679-1686.
[16] 王晶,郝燕燕.小梁切除术中应用羊膜与丝裂霉素C的比较[J].中华眼外伤职业眼病杂志,2015,37(5):361-364.
[17] 程美仙,胡小坤,罗添场.青光眼术中个性化使用丝裂霉素的疗效[J].中华眼外伤职业眼病杂志,2015,37(5):369-371.
[18] 钟毅敏,刘杏,张平,等.小梁切除术后薄壁滤过泡的临床及病理分析[J].眼科,2009,18(1):38-41.
[19] 邱艳飞,胡锡彬,何建中,等.青光眼小巩膜瓣小梁切除术后断巩膜缝线及眼球按摩调整眼压效果观察[J].现代医药卫生,2015,31(12):1841-1843.
[20] 殷雪,梁亚,袁志兰.miR-200a对结膜成纤维细胞增生和迁移的调控作用及其机制[J].中华实验眼科杂志,2016,34(12):1087-1091. |
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