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Clinical research of respiratory distress syndrome in late preterm infants |
DING Sufang LIU Yingying WU Rong▲ |
Neonatal Medical Center, Maternal and Child Healthcare Hospital of Huaian Affiliated to Yangzhou University Medical Academy, Jiangsu Province, Huaian 223002, China |
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Abstract Objective To investigate the incidence, risk factors, clinical features of respiratory distress syndrome (RDS) in the late preterm infants. Methods The clinical data of prematures who were hospitalized and cured in Maternal and Child Healthcare Hospital of Huaian Affiliated to Yangzhou University Medical Academy from January 2010 to December 2013 were retrospectively analyzed. All the prematures who ′s age were less than 72 hours and the gestational age were 34+1-36+6 weeks. Results Participants included 452 cases, RDS group was 152 cases and control group was 300 cases. The incidence rate of RDS in late preterm infants was 33.6% (152/452). There were no statistical significance of two groups in birth weight, gestational age, fetal time (P > 0.05). The rest of basic situation of two groups was compared, with statistical difference (P < 0.05).Incidence rate of premature rupture of membranes in RDS group was lower than that in control group (P < 0.05). Incidence rate of placental abnormality, fetal distress, CPAP, tracheal intubation, pulmonary hemorrhage, PPHN, gas leak, VAP and intracranial hemorrhage in RDS group were higher than those in control group (P < 0.05). Logistic regression analysis showed that the risk factors of RDS in the late preterm infants were premature rupture of memberane, cesarean elicery, elective caesarean section leaded by scar uterus and social factors (P < 0.05). Conclusion Late preterm infants with a higher incidence of RDS, heavier and more complications. The risk factors of RDS in the late preterm infants are premature rupture of memberane, cesarean elicery, elective caesarean section leaded by scar uterus and social factors.
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