快速康复外科理念对结直肠癌合并糖尿病患者术后应激反应及血糖水平的影响

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Abstract Objective To explore the influence of fast track surgery (FTS) on stress reaction and blood glucose level in the perioperative patients with colorectal cancer and diabetes mellitus. Methods A total of 124 patients with colorectal cancer and diabetes mellitus, who were admitted in the Second Hospital of Qinhuangdao from June 2013 to June 2016 were selected. All patients were divided into the control group (60 cases) and the observation group (64 cases) according to the perioperative treatment. The patients in the control group were performed with routine perioperative treatment, while the patients in the observation group were given FTS perioperative treatment. The defecation time, anal exhaust time, time of wallowing half-solid food in the two groups after operation were observed. And the stress reaction indexes (CRP, IL-6, Cor) and fasting blood glucose (FPG) level in the two groups before and after the operation were compared. Results The defecation time, anal exhaust time, time of wallowing half-solid food in the observation group were significantly shorter than those in the control group (P < 0.05). There were no significant differences in the levels of CRP, IL-6, Cor and FPG before operation in the two groups (P > 0.05), but after operation there were statistically significant differences between the two groups (P < 0.01); except the FPG in observation group on postoperative 3 day (P > 0.05), compared with before surgery of the above indicators, there were also significant differences in each group on postoperative 1 and 3 day(P < 0.01). Conclusion FTS concept used for the perioperative management of colorectal carcinoma complicated with diabetes mellitus, can reduce the stress response and the level of blood glucose, and accelerate the patients′ postoperative rehabilitation.

Key words： Colorectal cancer Diabetes mellitus Fast track surgery Perioperative period

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	HE Fang WANG Pingyun LI Xinghua CHANG Weiwei

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HE Fang WANG Pingyun LI Xinghua CHANG Weiwei. Influence of fast track surgery on postoperative stress reaction and blood glucose level in patients with colorectal cancer and diabetes mellitus [J]. 中国医药导报, 2017, 14(28): 69-73.

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http://www.yiyaodaobao.com.cn/EN/ OR http://www.yiyaodaobao.com.cn/EN/Y2017/V14/I28/69

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