星状神经节阻滞治疗偏头痛的有效性及安全性分析及其对头颈部动脉血流动力学的影响

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Abstract Objective To investigate the effectiveness and safety of stellate ganglion block (SGB) in the treatment of migraine and its influence on the hemodynamics of intracranial and cervical arteries. Methods Eighty patients met with the diagnostic criteria of migraine treated in Department of Pain, Sanbo Brain Hospital, Capital Medical University from June 2014 to January 2015 were selected. The pain degree was evaluated by numerical rating scale (NRS), the postoperative complications were recorded, and the efficacy was evaluated after operation for 6 months. The bilateral cervical arteries and intracranial arteries were detected by transcranial doppler sonography to record the indexes of hemodynamics. Results Compared with those before SGB, the scores of NRS after SGB were decreased, the difference was statistically significant (P ＜ 0.05). The total effective rate of SGB after 6 months was 91.25%. Compared with that before block and the opposite block side, SGB could significantly increase the diastolic flow velocities of the block side of external carotid artery and common carotid artery, decrease the pulse index, the differences were all statistically significant (P ＜ 0.05). The blood flow velocities, the changes of flow velocities and the pulse indexes of the block side and the opposite block side of the other cervical arteries and intracranial arteries had no statistically significant differences before and after SGB (P ＞ 0.05). After SGB, among 80 cases of patients, there were 6 cases (7.50%) with hoarseness (completely disappeared within 1 h), 2 cases (2.50%) with transient upper limb numbness, 3 cases (3.75%) with brachial plexus block, 4 cases (5.00%) with puncture site pain, 3 cases (3.75%) with foreign body sensation. Conclusion SGB is efficacious and safe to treat migraine. SGB can relieve the symptoms of migraine may be achieved by lowering the vascular resistance of external carotid artery and common carotid artery, speeding up their blood flow velocity, and mildly lowering the vascular resistance of intracranial arteries.

Key words： Migraine Stellate ganglion block Effectiveness Safety Hemodynamics

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	WANG Huiying1
	2 LI Hongliang3 WANG Baoguo1

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WANG Huiying1,2 LI Hongliang3 WANG Baoguo1. Analysis on the effectiveness and safety of stellate ganglion block in the treatment of migraine and its influence on the hemodynamics of intracranial and cervical arteries[J]. 中国医药导报, 2017, 14(21): 25-28,49.

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http://www.yiyaodaobao.com.cn/EN/ OR http://www.yiyaodaobao.com.cn/EN/Y2017/V14/I21/25

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