住院患者多种慢性疾病与骨质疏松症的偏相关分析

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Abstract Objective To discuss the correlation between osteoporosis and various chronic diseases in the elderly. Methods 373 patients in Geriatrics Department of 181th Hospital of PLA from April 2013 to September 2016 were selected as the whole patients, in which the elderly patients over 60 years old were selected as the elderly. Within 24 hours of admission, age, sex , height and BMI, at the same time, according their anamnesis and hospital examination, whether suffered from common chronic diseases such as type-2 diabetes, hypertension, coronary heart disease, COPD, cerebral apoplexy, malnutrition, chronic kidney disease, cataract, spinal degeneration, urinary tract stones and biliary calculi of these patients were investigated. The BMD of L2-L4, bilateral collum femoris, oblique eminence of cuboid bone and Ward′s triangle were measured, the low values of T-scores were taken. Then the relation between the foregoing investigation′s data and BMD in all patients and the elderly were analyzed by partial correlation analysis. Results Partial correlation analysis showed that in all patients BMD was related with sex, age, BMI, type-2 diabetes, stroke, cataracts, thoracic vertebra degeneration, knee-joint degeneration, biliary calculi (P < 0.05). But in the elderly, the BMD was related with sex, BMI, type-2 diabetes, hypertension, coronary heart disease, cerebral apoplexy, knee-joint degeneration, biliary calculi (P < 0.05). Conclusion BMD is related with multiple factors and various chronic diseases such as gender, BMI, type-2 diabetes, stroke , knee-joint degeneration, biliary calculi and so on, meanwhile, BMD in the elderly is related to hypertension and others, which prompts that prevention and treatment of these chronic diseases may contribute to osteoporosis.

Key words： Osteoporosis Chronic diseases Partial-correlation analysis

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	ZHAO Lei LIU Xueyuan CHEN Richao HE Jie LU Shuihuan LIAO Li LI Cheng

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ZHAO Lei LIU Xueyuan CHEN Richao HE Jie LU Shuihuan LIAO Li LI Cheng. Partial correlation analysis of various chronic disease and osteoporosis in hospitalized patients[J]. 中国医药导报, 2017, 14(28): 53-56.

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http://www.yiyaodaobao.com.cn/EN/ OR http://www.yiyaodaobao.com.cn/EN/Y2017/V14/I28/53

[1] 黄淑纡，林华.老年性骨质疏松性骨折的发生与预防[J].中国骨质疏松杂志，2012，4（18）：381-385.
[2] R?kel A，Sheehy O，Rahme E，et al. Osteoporosis amongpatients with type 1 and type 2 diabetes [J]. Diabetes Metab，2008，34（3）：193-205.
[3] Rathmann W，Kostev K. Fracture risk in patients with newly diagnosed type 2 diabetes：a retrospective database analysis in primarycare [J]. J Diabetes Complications，2015， 29（6）：766-770.
[4] 刘学员，邓泽熙，林仁生，等.激素对糖尿病及无糖尿病老年患者骨质疏松的影响[J].中华临床医师杂志：电子版，2016，10（23）：3516-3520.
[5] 刘帼静，呼晓雷，何发忠，等.2型糖尿病骨质疏松研究进展[J].中国药理学通报，2016，32（10）：1333-1336.
[6] 张海林，孙惠清，倪卓民，等.绝经后妇女膝关节骨|生关节炎和骨质疏松症发生率关系[J].中国骨质疏松杂志，2016，4（22）：463-465.
[7] 雷映红，杨群芳，陈星霖，等.老年人群代谢综合征与骨密度的相关性研究[J].中国临床保健杂志，2012，15（6）：576-578.
[8] Mpalaris V，Anagnostis P，Goulis DG，et al. Complex association between body weight and fracture risk in postmenopausal women [J]. Obes Rev，2015，16（3）：225-233.
[9] 贺琳，黄力.高血压病与原发性骨质疏松症的相关研究[J].北京中医药大学学报，2008，15（2）：1.
[10] 刘颖，宋成伟，杜以武.老年人原发性高血压与骨密度及骨代谢失调的相关性研究[J].中国实验诊断学，2014， 18（10）：1689-1690.
[11] Nakagami H，Morishita R. Hypertension and osteoporosis [J]. Clinical Calcium，2013，23（4）：497.
[12] 刘康妍，胡海澜，陈勇，等.股四头肌肌力及骨质疏松与膝骨关节炎的关系[J].中华关节外科杂志，2016，10（3）：271-276.
[13] 李丽辉，杨杰，董洁琼，等.运动对去卵巢大鼠OPG RANKL表达的影响[J].中国运动医学杂志，2013，32（11）：991-996.
[14] 贾晓静，贾少杰.脑卒中与骨质疏松的相关性[J].中国老年学杂志，2012，10（32）：4267-4268.
[15] Szu H，Noel S，Yim SB，et al. Multimedia authenticity protection with ICA watermarking and digital bacteria vaccination [J]. Neural Netw，2003，16（5-6）：907-914.
[16] 刘勇.枣庄市≥50岁人群白内障患病率及危险因素分析[J].中华全科医学，2014，12（7）：1115-1117.
[17] Hashim Z，Zarina S. Osmotic stress induced oxidative damage：possible mechanism of cataract formation in diabetes [J]. J Diabetes Complications，2012，26（4）：275-279.
[18] Klahan S，Kuo CN，Chien SC，et al. Osteoporosis increase risk of gallstone ：a nationwide population based cohort study in Taiwan [J]. BMC Gastroenterol，2014，14（1）：192.
[19] Shavit L，Girfoglio D，Vijay V，et al. Vascular calcification and bone mineral density in recurrent kinder stone formers [J]. Clin J Am Soc Nephrol，2015，10（2）：278-285.
[20] Sarkar M，Bhardwaj R，Madabhavi I，et al. Osteoporosis in chronic obstructive pulmonary disease [J]. Clin Med Insights Circ Respir Pulm Med，2015，9：5-21.
[21] Clancy J，Nobes M. Chronic obstructive pulmonary disease：Nature—nurture interactions [J]. Br J Nurs，2012，21（13）：772-781.
[22] 郑婧，幕广建，邹继红，等.低骨密度与老年冠心病关系的研究[J].中国骨质疏松杂志，2014，20（10）：1212-1215.
[23] 孙承功，王寅，朱频，等.骨量水平与老年冠心病患者颈动脉内膜中层厚度的相关性研究[J].疑难病杂志，2017， 16（4）：329-331，335.DOI：10.3969/j.issn.1671-6450.2017. 04.002.
[24] 陈辉，王新杰，袁盛平，等.二仙汤经皮给药治疗老年人骨质疏松症的临床研究[J].中国医药科学，2016，6（5）：65-67.
[25] 谢莲娜，钟雪焱，王丽君，等.阿托伐他汀钙对老年冠心病患者骨密度的影响[J].临床心血管病杂志，2008，24（2），103-105.
[26] 代宁，燕鹏，张忱忱，等.糖尿病合并骨质疏松症相关危险因素分析[J].中国医药导报，2016，13（18）：69-71，84.
[27] 胡德洪，何斌，彭仲华，等.佛山市三水地区老年人骨质疏松性骨折危险因素调查与分析[J].中国医药科学，2016， 6（24）：154-157.DOI：10.3969/j.issn.2095-0616.2016. 24.049.
[28] 刘晓梅，谭春梅，梁庆华，等.中老年人慢性代谢性疾病相关代谢指标的研究[J].中国医药导报，2016，13（30）：20-22，28.
[29] Hatzigeorgiou C，Jackson JL. Hydroxymethylglutaryl-coenzyme A reductase inhibitors and osteoporosis：a meta-analysis [J]. Osteoporos Int，2005，16（8）：990-998.