|
|
A randomized controlled trial on total resection and subtotal resection for supratentorial gliomas associated with epilepsy |
WANG Jun1 ZHANG Jie1,2 WU Jianbing1,2 |
1.Department of Neurosurgery, Ya′an People′s Hospital, Sichuan Province, Ya′an 625000, China;
2.Department of Neurosurgery, Chengdu 363 Hospital, Southwest Medical University, Sichuan Province, Chengdu 610041, China |
|
|
Abstract Objective To compare the clinical effect of total resection and subtotal resection in the treatment of supratentorial gliomas with epilepsy. Methods A total of 56 patients with supratentorial glioma and epilepsy were admitted to Ya′an People′s Hospital from April 2016 to April 2017, 28 cases in each group. Total tumor resection was performed in the observation group and subtotal tumor resection was performed in the control group. Epilepsy control, Karnofsky performance status (KPS) score, complications were compared between the two groups. Results The satisfaction rate of epilepsy control in the observation group was significantly higher than that in the control group (P < 0.05), and the KPS score in the observation group at 3 months and 1 year after operation were higher than those in the control group (P < 0.05). The complications of the two groups had no statistically significant difference (P > 0.05). Conclusion Total resection for supratentorial glioma with epilepsy has the same effect as subtotal resection, but it can improve the satisfaction rate of epilepsy control, improve the quality of life, reduce the recurrence rate and it has high clinical value.
|
|
|
|
|
[1] 邢海涛,袁波,娄志刚,等.肿瘤全切术治疗颞叶胶质瘤继发癫痫的疗效及安全性观察[J].中国实用神经疾病杂志,2016,19(11):118-119.
[2] 吴祖超,张建海,严衍庆.低级别胶质瘤53例临床特点及预后分析[J].福建医药杂志,2016,38(1):32-34.
[3] 岳向勇,武江,郭韬.多模态影像神经导航联合术中超声在切除颅内胶质瘤中的应用[J].第三军医大学学报,2018, 40(7):620-624.
[4] 谢海涛,隋立森,陈忠平,等.合并癫痫的低级别胶质瘤患者的癫痫外科治疗[J].广东医学,2017,38(10):1545-1547.
[5] 杨卓,王新军,单峤,等.胶质瘤相关性癫痫患者术后痫性再发的临床特征及影响因素[J].医学研究生学报,2017, 30(4):405-408.
[6] 毛捷,沈军,钱冬喜,等.边缘系统胶质瘤的临床分型及显微手术治疗[J].皖南医学院学报,2016,35(4):330-332.
[7] Francione S,Liava A,Mai R,et al. Drug-resistant parietal epilepsy:polymorphic ictal semiology does not preclude good post-surgical outcome [J]. Epileptic Disord,2015,17(1):32-46.
[8] 方富,林元相,康德智,等.以癫痫为首发症状的低级别胶质瘤患者的手术疗效及预后影响因素[J].中华医学杂志,2016,96(13):1031-1034.
[9] 李珊,陈建新,李岩,等.恶性神经胶质瘤脑膜 脊髓播散转移15例临床病例分析[J].中国肿瘤临床,2016,43(6):260-264.
[10] 乌拉别克·毛力提,艾克拜尔·亚里坤,杨小朋.颞叶占位性病变伴癫痫患者的手术治疗研究[J].中国实用神经疾病杂志,2016,19(13):15-16.
[11] 张波,王宇.脑胶质瘤术后放疗患者预后影响因素分析[J].现代中西医结合杂志,2016,25(18):2011-2013.
[12] 王强,朱玉辐,沈志刚,等.神经节细胞胶质瘤的临床特点及外科治疗[J].临床神经外科杂志,2016,13(5):332-334.
[13] 梁韡斌,张高炼,韦可聪,等.颞叶节细胞胶质瘤相关癫痫的临床特点及手术疗效[J].广西中医药大学学报,2016, 19(1):56-58.
[14] Chou CC,Shih YH,Yen DJ,et al. Long-term health-related quality of life in drug-resistant temporal lobe epilepsy after anterior temporal lobectomy [J]. Epileptic Disorders,2015,17(2):177-183.
[15] 黎珊,张纬建,蔡传书,等.基于磁共振指导靶区勾画的高级别胶质瘤术后调强放射治疗的疗效分析[J].中华放射医学与防护杂志,2017,37(10):767-770.
[16] 哈斯木江·热合曼,杨小朋.脑胶质瘤术后早期癫痫发生现状及危险因素分析[J].癌症进展,2017,15(8):947-949.
[17] 谢玉环,王天舒,丁丽丽.脑胶质瘤患者术后不同时间段的生存质量分析[J].安徽医药,2017,21(9):1656-1659.
[18] 周苏娜,张琰君,何东杰,等.低级别胶质瘤36例患者术后放疗的预后分析[J].山西医科大学学报,2016,47(9):847-850.
[19] 胡珊,陈春辉,丁文谦.皮层电极脑电监测在致痫性胶质瘤术中的应用[J].中国医疗器械信息,2016,22(9):15-16.
[20] 邱军,郭良波,高峰,等.87例低级别胶质瘤的临床病理特点与预后分析[J].中国医师进修杂志,2017,40(3):204-207. |
|
|
|