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Advances of functions of IQGA3 and its research on tumor |
LI Yafang XU Min |
Department of Gastroenterology, Affiliated Hospital of Jiangsu University, Jiangsu Province, Zhenjiang 212013, China |
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Abstract IQGAP3 is a newly discovered member of the scaffold protein family. By interacting with its target proteins, IQGAP3 participates in many signaling pathways and regulation cellular function. In recent years, many studies have found that IQGAP3 plays an important role in tumorigenesis and development by promoting tumor cell proliferation, enhancing cell invasion and reducing intercellular adhesion.
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