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| Comparison the effect of balloon dilatation alone and combination with drug eluting stent implantation in treatment of infrapopliteal arterial occlusive disease |
| WU Zhongjian GU Yongquan▲ QI Lixing GUO Lianrui CUI Shijun LI Jianxin YANG Shengjia TONG Zhu |
| Department of Vascular Surgery, Xuanwu Hospital, Capital Medical University Vascular Surgery Research Institution of Capital Medical University, Beijing 100053, China |
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Abstract Objective To compare and analyze the efficacy of balloon dilatation alone and combination with drug eluting stent implantation in the treatment of infrapopliteal arterial occlusive disease. Methods The clinical data of 126 patients (139 limbs) with infrapopliteal arterial occlusive disease and underwent the endovascular treatment from March to 2013 and October 2015 in Xuanwu Hospital, Capital Medical University were retrospectively analyzed. All the cases received balloon dilatation therapy at first, and 32 limbs among them received the drug-eluting stent implantation in infrapopliteal artery. After the surgery, the improvement of symptoms, the change of ankle brachial indexes, changes of vascular ultrasonic images, the limb salvage rate and recent patency rate and so on were observed. Results 8 patients (10 limbs) failed, and the ankle brachial index (ABI) of successful cases increased from before surgery (0.39±0.13) to 3 days after the surgery (0.82±0.16) (P < 0.05). Overall infrapopliteal arterial patency rate 6 months after the operation was 83.5% (101/121), and 12 months after operation was 69.5% (57/82), the patency rates of those with balloon dilatation alone were 83.3% (75/90) and 71.0% (44/62) respectively, the patency rates of those with stent implantation were 83.9% (26/31) and 65.0% (13/20) respectively, there were no statistical difference in efficacy between balloon dilation alone and stent implantation 6 months and 12 months after operation (P > 0.05 ). Conclusion Both endovascular interventional therapy with drug eluting stent implantation and balloon dilatation alone can be used to treat infrapopliteal arterial occlusive disease and they are with similar short-term efficacy. If there are severe complications that affect the blood flow in the treatment of infrapopliteal arterial disease, stent implantation should be considered to improve limb blood flow, avoid the complications and improve the limb salvage rate.
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