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| Effect of follicle flushing on embryonic developmentoflong protocol controlled ovarian hyperstimulation in vitro fertilization |
| JING Xia1 FENG Zhonghai2 WEI Bing1 CHEN Bi1 PENG Cailing1 ZOU Lin1 LI Yunqing1 HUANG Riyan1 MA Tianzhong1▲ |
1.Reproductive Medicine Center, Affiliated Hospital of Guangdong Medical University, Guangdong Province, Zhanjiang 524001, China;
2.Department of Quality Control, Zhanjiang Prevention and Treatment Center for Occupational Diseases, Guangdong Province, Zhanjiang 524001, China |
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Abstract Objective To evaluate the effects of follicle flushing on embryonic development in patients of long protocol controlled ovarian hyperstimulation in vitro fertilization. Methods From July 2014 to June 2016, in Reproductive Medicine Center, Affiliated Hospital of Guangdong Medical University, the clinical data of 343 patients underwent in vitro fertilization (IVF) were analyzed retrospectively. Among them，99 patients treated with G-MOPs were set as follicle flushing group, and 244 patients sucked direethy folliculer fluid were as control group. The oocyte retrieval rate, fertilization rate, 2PN cleavage rate, good quality embryo rate, blastocyst rate, available embryo rate, clinical pregnancy rate, implantation rate, abortion rate of two groups were compared. Results The available embryo rate, good quality embryo rate and blastocyst rate in follicle flushing group were higher than those in control group, the differences were statistically significant (P < 0.05), and other clinical and lab indication also checking had no statistical difference between the two groups (P > 0.05). Conclusion Follicle flushing is not necessary to increase the oocyte retrieval rate, but can increase the available embryo rate, good quality embryo rate and blastocyst rate, it showes a increased tendency gradually of clinical pregnancy rate and implantation rate.
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