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| Analysis of the rule of traditional Chinese medicine decoction in the treatment of carotid atherosclerosis |
| ZHANG Wenjiang1,2 YI Jian3 LIU Baiyan1 |
1.Hu'nan University of Chinese Medicine, Hu′nan Province, Changsha 410208, China;
2.Pathology Teaching and Research Section, Yiyang Medical College, Hu′nan Province, Yiyang 413000, China;
3.Central Laboratory, the First Hospital of Hu′nan University of Chinese Medicine, Hu′nan Province, Changsha 410007, China |
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Abstract Objective To explore the medication rules of traditional Chinese medicine in the treatment of carotid atherosclerosis. Methods The articles about carotid atherosclerosis were collected by using Wanfang, VIP and CNKI from January 2005 to December 2017. A total of 109 articles were up to the requirements at last. Then the articles were selected and put into software excel to establish a database. The TCM medication rule was analyzed by SPSS statistical software, including the frequency of the drugs being used, rate, four nature of drugs, five flavours, channel tropism, drug category, as well as the therapeutic principle and method. Results Total 147 Chinese herbal medicines were used in the literatures, the total frequency was 1007 times. The most frequently used TCM medications were Radix Salviae Miltiorrhizae, Rhizoma Ligustici Chuanxiong, Radix Astragali seu Hedysari. The main drug properties were warm, calm and cold, the cumulative frequency was 92.3%. The main characters of the five flavors were sweet, bitter, pungent, the cumulative frequency was 90.4%. The main channel tropisms of the drugs were liver, spleen and heart, the cumulative frequency was 86.4%. The main types of drugs were blood-activating and stasis-removing drugs, qi-tonifying drugs, blood-tonifying drugs and warmly resolving cold-phlegm drugs, the cumulative frequency was 45.1%. Conclusion The treatment of carotid atherosclerosis with Chinese medicine decoction is mainly based on activating blood circulation to dissipate blood stasis.
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