非编码RNA与急性肾损伤相关性的研究进展

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Abstract Acute kidney injury (AKI) is a common serious disease characterized by rapid decline in renal function and high mortality. However, the molecular mechanism of AKI is still unclear and there is no effective treatment. Non-coding RNA (ncRNAs) participate in the pathophysiological process of AKI by regulating inflammatory response, programmed cell death and cell cycle in repair phase. Therefore, a variety of ncRNAs are not only considered as new biomarkers of AKI, but also potential therapeutic targets. This article reviews the changes, functions and potential therapeutic effects of ncRNAs in AKI.

Key words： Non-coding RNA Acute kidney injury Biomarker Research progress

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	WANG Litao1
	2 LIAN Xingji3 TAN Ning2 LIU Yuanhui2

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WANG Litao1,2 LIAN Xingji3 TAN Ning2 LIU Yuanhui2. Research progress on the relationship between non-coding RNA and acute kidney injury[J]. 中国医药导报, 2019, 16(13): 38-41.

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http://www.yiyaodaobao.com.cn/EN/ OR http://www.yiyaodaobao.com.cn/EN/Y2019/V16/I13/38

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