|
|
|
| A case report of acute febrile neutrophilic dermatosis |
| OU Mei WU Hongmei LUO Yuanyuan LU Mao |
| Department of Dermatology, the First Affiliated Hospital of Chengdu Medical College, Sichuan Province, Chengdu 610500, China |
|
|
|
|
Abstract The clinical manifestations of acute febrile neutrophilic dermatosis are painful red plaques or nodules, usually accompanied by fever and increased peripheral white blood cell count, percentage of neutrophils, erythrocyte sedimentation rate and C-reactive protein. Its histopathological expression is an inflammatory vascular response mainly infiltrated by neutrophils in the dermis. Acute febrile neutrophilic dermatosis is a rare skin disease that is easily misdiagnosed. To explore the clinical characteristics, differential diagnoses and treatments of acute febrile neutrophilic dermatosis, this paper reports a patient with acute febrile neutrophilic dermatosis treated in the First Affiliated Hospital of Chengdu Medical College, including his clinical and laboratory examination features and the process of diagnoses and treatments. The results indicate that to improve the definite diagnosis rate of acute febrile neutrophilic dermatosis, the clinician should attach importance to the histopathological biopsy and collect samples in multiple sites timely and repeatedly.
|
|
|
|
|
|
[1] Sweet RD. An acute febrile neutrophilic dermatosis [J]. Br J Dermatol，1964，76：349-356.
[2] 张学军.皮肤性病学[M].8版.北京：人民卫生出版社，2013：174.
[3] 赵辨.中国临床皮肤病学[M].2版.南京：江苏凤凰科学技术出版社，2017：979-982.
[4] Odom RB，James WD，Berger TG. Andrews’ diseases of the skin [M]. Ninth edition. Harcourt Asia：W.B. Saunders，2001：155-157.
[5] Husein-Elahmed H，Fernandez-Pugnaire MA. Tender erythematous plaques on legs [J]. Ann Acad Med Singapore，2013，42（5）：259-260.
[6] Chen KR，Carlson JA. Clinical approach to cutaneous vasculitis [J]. Am J Clin Dermatol，2008，9（2）：71-92.
[7] Caucanas M，Heylen A，Rolland F，et al. Associated pyoderma gangrenosum，erythema elevatum diutinum，and Sweet’s syndrome：the concept of neutrophilic disease [J]. Int J Dermatol，2013，52（10）：1185-1188.
[8] Davatchi F，Chams-Davatchi C，Shams H，et al. Behcet’s Disease：epidemiology，clinical manifestations，and diagnosis [J]. Expert Rev Clin Immunol，2017，13（1）：57-65.
[9] Bakelants E，Van DHJ，Corluy L，et al. The diagnostic tangle of pyoderma gangrenosum：a case report and review of the literature [J]. Neth J Med，2014，72（10）：541-544.
[10] 高天文，孙建方.现代皮肤组织病理学[M].北京：人民卫生出版社，2001：147-153.
[11] Gupta S，Handa S，Kanwar AJ，et al. Cutaneous vasculitides：clinico-pathological correlation [J]. Indian J Dermatol Venereol Leprol，2009，75（4）：356-362.
[12] Braswell SF，Kostopoulos TC，Ortega-Loayza AG. Pathophysiology of pyoderma gangrenosum （PG）：an updated review [J]. J Am Acad Dermatol，2015，73（4）：691-698.
[13] Hassikou H，Tabache F，Baaj M，et al. Sweet’s syndrome in Behcet’s disease [J]. Joint Bone Spine，2007，74（5）：495-496.
[14] Amouri M，Masmoudi A，Ammar M，et al. Sweet’s syndrome：a retrospective study of 90 cases from a tertiary care center [J]. Int J Dermatol，2016，55（9）：1033-1039.
[15] Abbas O，Kibbi A，Rubeiz N. Sweet’s syndrome：retrospective study of clinical and histologic features of 44 cases from a tertiary care center [J]. Int J Dermatol，2010， 49（11）：1244-1249.
[16] 甘雨舟，黄文祥，甘华.伴有脂膜炎样皮损的Sweet综合征1例[J].重庆医学，2015，44（3）：431-432.
[17] Cooper PH，Frierson HF，Greer KE. Subcutaneous neutrophilic infiltrates in acute febrile neutrophilic dermatosis [J]. Arch Dermatol，1983，119（7）：610-611.
[18] Chan MP，Duncan LM，Nazarian RM. Subcutaneous Sweet syndrome in the setting of myeloid disorders：a case series and review of the literature [J]. J Am Acad Dermatol，2013， 68（6）：1006-1015.
[19] El-Khalawany M，Aboeldahab S，Mosbeh AS，et al. Clinicopathologic，immunophenotyping and cytogenetic analysis of Sweet syndrome in Egyptian patients with acute myeloid leukemia [J]. Pathol Res Pract，2017，213（2）：143-153. |
|
|
|
