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A meta-analysis of evaluation of contrast-enhanced CT for renal space-occupying lesions |
YANG Xue HU Yong LUO Hechuan |
Department of Radiology, Yongchuan Hospital Affiliated to Chongqing Medical University, Chongqing 402160, China |
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Abstract Objective To systematically review the cIinical value of contrast-enhanced CT (CECT) in diagnosis of renal space-occupying lesions. Methods Literatures concerning contrast-edhanced CT diagnosis of renal space-occupying lesions published from January 2008 to April 2018 were electronically searched in the databases including PubMed, Cochrane Library, Embase, CNKI, VIP and CBM. Statistical analysis were performed via Metadisc 1.4 and Stata 15.1 software, and QUADAS scale was used to evaluate the quality of the enrolled literatures. Results Totally 17 literatures that met the standards were inrolled incIuding 1099 renal space-occupying lesions cases in total. The heterogeneity of the study group was obvious, so the random effect model was adopted. The combined sensitivity (SEN), combined specificity (SPE), diagnostic ratio (DOR), positive likelihood ratio (+LR), negative likelihood ratio (-LR), area under SROC curve (AUC) and Q index of the renal space-occupying lesions diagnosed by CECT were 0.85(95%CI: 0.82-0.87), 0.68(95%CI: 0.62-0.74), 11.30(95%CI: 6.53-19.55), 2.34(95%CI:1.84-2.97), 0.24(95%CI:0.17-0.32), 0.8489, 0.7801. Conciusion CECT is effective in the diagnosis of benign and malignant renal space-occupying lesions.
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