益胃活血汤治疗气滞血瘀型急性胃炎的临床效果

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Abstract Objective To analyze the clinical efficacy of Yiwei Huoxue Decoction in the treatment of acute gastritis patients with syndrome of qi stagnation and blood stasis. Methods One hundred and twenty acute gastritis patients with syndrome of qi stagnation and blood stasis admitted to Wangjing Hospital of China Academy of Chinese Medical Sciences from February 2016 to December 2017 were selected and divided into two groups by random number table method. 60 patients in the control group were treated with conventional Western medicine, 60 patients in the observation group were added with Yiwei Huoxue Decoction on the basis of Western medicine. After 2 weeks of continuous treatment, the clinical efficacy and TCM symptom scores, the levels of gastrin and motilin, and the safety were compared between the two groups. Results The scores of Shangwan pain, loss of appetite and vomiting or hematemesis in the observation group and the control group were all lower than those before treatment (t = 20.612, 22.796, 19.474, all P ＜ 0.05; t = 16.095, 18.724, 15.163, all P ＜ 0.05), and the scores of Shangwan pain, loss of appetite and vomiting or hematemesis in the observation group were lower than those of the control group after treatment (t = 10.067, 14.858, 13.267, all P ＜ 0.05). The total effective rate of the observation group was higher than that of the control group, the difference was statistically significant (χ2 = 5.55, P ＜ 0.05). The levels of gastrin and motilin in the observation group and the control group were alll higher than those before treatment (t = 5.353, 11.277, all P ＜ 0.05; t = 2.715, 5.571, all P ＜ 0.05), and the levels of gastrin and motilin in the observation group were alll higher than those of the control group, the differences were statistically significant (t = 11.727, 20.782, all P ＜ 0.05). The total incidence of adverse reactions in the observation group was lower than that in the control group (χ2 = 11.36, P ＜ 0.05). Conclusion Yiwei Huoxue Decoction can effectively improve the symptoms and gastrointestinal function of acute gastritis patients with syndrome of qi stagnation and blood stasis, it is safe and reliable, and it has significant application value.

Key words： Yiwei Huoxue Decoction Syndrome of qi stagnation and blood stasis Acute gastritis TCM symptom score

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	NIU Ran WEI Wei▲ SUN Xiaohong GUO Yu LIU Yaxin

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NIU Ran WEI Wei▲ SUN Xiaohong GUO Yu LIU Yaxin. Clinical effect of Yiwei Huoxue Decoction in treating acute gastritis with syndrome of qi stagnation and blood stasis[J]. 中国医药导报, 2019, 16(10): 124-127.

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http://www.yiyaodaobao.com.cn/EN/ OR http://www.yiyaodaobao.com.cn/EN/Y2019/V16/I10/124

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