反流性食管炎与代谢综合征相关因素的关系

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Abstract Objective To investigate the relationship between reflux esophagitis (RE) and related factors of metabolic syndrome. Methods From November 2016 to March 2018, 176 patients who underwent endoscopy at the endoscopy center of Renmin Hospital of Wuhan University and were diagnosed with RE were enrolled as RE group. And 331 patients with normal gastroscopy or only mild chronic superficial gastritis in the same period were selected as control group. General information and past history were collected. Abdominal ultrasonography and blood biochemical tests were performed in both groups. The differences of age, sex, body mass index (BMI), detection rate of nonalcoholic fatty liver disease (NAFLD), smoking rate, prevalence rate of hypertension, blood sugar, blood lipid and other independent risk factors between the two groups and the independent risk factors for RE were analyzed. Results The percentage of males, BMI, NAFLD detection rate, smoking rate, prevalence of hypertension, alanine transferase, fasting blood sugar and triglyceride levels in RE group were significantly higher than those in the control group (P < 0.05), and the level of high density lipoprotein was significantly lower than that in the control group (P < 0.05). Male, overweight and hypertension were independent risk factors for RE (OR = 2.274, 3.389, 2.145, P < 0.05). Conclusion Male, overweight and hypertension are the risk factors of RE, which should be paid attention to in clinical prevention and treatment.

Key words： Reflux esophagitis Metabolic syndrome Nonalcoholic fatty liver disease Overweight Hypertension Risk factors

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	CHENG Yi′an TAN Shiyun LI Ming LU Mingjun

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CHENG Yi′an TAN Shiyun LI Ming LU Mingjun. Relationship between reflux esophagitis and related factors of metabolic syndrome[J]. 中国医药导报, 2019, 16(10): 92-95.

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http://www.yiyaodaobao.com.cn/EN/ OR http://www.yiyaodaobao.com.cn/EN/Y2019/V16/I10/92

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