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Systematic review of the effects of cognitive behavioral therapy on quality of life and depression of informal caregivers of patients with cancer |
ZHANG Ping ZHANG Xiaoman CHEN Lijun YIN Yongtian WU Qiong WANG Bo |
School of Nursing, Shandong University of Traditional Chinese Medicine, Shandong Province, Ji′nan 250355 |
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Abstract Objective To systematically evaluate the effects of cognitive behavioral therapy on the quality of life and depression of informal caregivers of patients with cancer. Methods Computer was used to search the Chinese and English databases of PubMed, the Cochrane Library, CINAHL, EMBASE, CBM, CNKI, Wanfang, VIP, etc. systematically, to collect literature on cognitive behavioral therapy for the quality of life and depression of informal caregivers of patients with cancer. The searching time was from the establishment of the database to July 2018. Two researchers conducted screening, data extraction, and quality evaluation based on inclusion and exclusion criteria, and used Review Manager 5.3 for meta-analysis. Results A total of 8 randomized controlled trials were included. There were 946 informal caregivers of patients with cancer, 44 patients quitted due to halfway or other reasons, and 902 patients completed interventions, including 452 patients in the intervention group and 450 patients in the control group. The intervention group received cognitive behavioral therapy intervention. There was significant difference in quality of life between intervention group and control group [MD = 20.15, 95%CI: 5.15-35.15, P = 0.008]. Cognitive behavioral therapy could improve depression of informal caregivers of patients with cancer. Conclusion Cognitive behavioral therapy can improve the depression and quality of life of informal caregivers of patients with cancer.
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