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The efficacy of Etoricoxib and Glucosamine Hydrochloride Capsules combined with kinesitherapy in the treatment of knee osteoarthritis |
MA Chunfang YANG Qiong |
Clinical Pharmacology Room, Ningbo No.6 Hospital of Zhejiang Province, Zhejiang Province, Ningbo 315040, China |
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Abstract Objective To explore the efficacy of Etoricoxib and Glucosamine Hydrochloride Capsules combined with kinesitherapy in the treatment of knee osteoarthritis. Methods A total of 219 clinical data of patients with knee osteoarthritis in Ningbo No.6 Hospital of Zhejiang Province from January 2016 to June 2017 were retrospectively analyzed and divided into the control group (99 cases, treated with Glucosamine Hydrochloride Capsules) and the observation group (120 cases, treated with Etoricoxib and Glucosamine Hydrochloride Capsules combined with kinesitherapy) by different treatment methods. The western Ontario and McMaster university osteoarthritis index (WOMAC), hospital of special surgery (HSS), visual analogue scale(VAS), five repetition sit-to-stand test(FTSST) and total effective rate of the two groups were compared. Results There were no statistically significant differences in the pain, stiffness, the scores of daily activity level, HSS, VAS and FTSST in the two groups before treatment (P > 0.05). After treatment, the pain, stiffness, scores of daily activity level, VAS and FTSST in the two groups were lower than those of before treatment and the score of HSS was higher than that of before treatment, the indicators above in the observation group changed more significantly, with statistically significant differences (P < 0.05). The total effective rate in the observation group was higher than that of control group, with statistically significant differences(P < 0.05). Conclusion The clinical symptoms in the patients of knee osteoarthritis treated with Etoricoxib and Glucosamine Hydrochloride Capsules combined with kinesitherapy is improved significantly. The efficacy is good. It is worthy of promotion and application.
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