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Study on arthroscopy debridement combined with Shenjin Tougu Decoction in the treatment of knee osteoarthritis |
XIANG Fusheng1 LIU Li1 ZHOU Bin1 WANG Jing1 YIN Guoliang2 YU Guihua1 YANG Dongxiao3 WU Jianhui1 |
1.Department of Orthopaedic, Ezhou Central Hospital, Hubei Province, Ezhou 436000, China;
2.Department of Traditional Chinese Medicine, Ezhou Central Hospital, Hubei Province, Ezhou 436000, China;
3.Department of Medical Imaging, Ezhou Central Hospital, Hubei Province, Ezhou 436000, China |
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Abstract Objective To study the clinical effect of arthroscopic debridement combined with Shenjin Tougu Decoction in the treatment of knee osteoarthritis. Methods A total of 526 cases with mild-to-moderate knee osteoarthritis in Ezhou Central Hospital from February 2010 to February 2015, which were randomly divided into observation group 263 cases and control group 263 cases by random number table method. The observation group was treated with arthroscopy debridement combined with the fumigation and washing with Shenjin Tougu Decoction, the control group was treated with arthroscopy debridement simply. Criteria for judging the therapeutic effect of knee osteoarthritis Japanese orthopaedic association scores (JOA) and hospital for special surgery knee score (HSS) knee scoring criteria were used to evaluate curative effect postoperative 49, 91, 175 days. Results There was no significant difference in HSS and JOA excellent and good rates between the two groups at 49th day after surgery (P > 0.05). At 91st and 175th day after surgery, HSS and JOA excellent and good rates in the observation group were higher than those in the control group, and the differences were statistically significant (P < 0.05). There were no severe adverse reactiows in the two groups. Conclusion Application of combined arthroscopy debridement and Shenjin Tougu Decoction fumigation in the treatment of knee osteoarthriti had better long-term curative effect than simply using arthroscopy debridement. Shenjin Tougu Decoction in long term can relieve patients′ pain and delay the progress of articular degeneration, and improve patients′ quality of life.
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[1] 王晶,向福胜,刘丽,等.膝关节骨性关节炎的中西医结合治疗进展[J].中国医药导报,2018,15(6):35-38,48.
[2] 陈艳平,陈蓓,郑英杰,等.膝关节骨性关节炎诊断的研究进展[J].湖南中医杂志,2017,33(5):189-193.
[3] 骨关节炎诊治指南(2007年版)[J].中国矫形外科杂志,2014,22(3):287-288.
[4] 卫彦强,石继祥,纪斌,等.骨性关节炎发病机制的研究进展[J].医学综述,2018,24(5):838-842.
[5] 王伟民,刘红军,石晶.关节镜联合应用盐酸氨基葡萄糖治疗轻中度骨性关节炎[J].临床骨科杂志,2013,16(1):114-115.
[6] 辛雷,苏佳灿.膝关节功能评分:现状与展望[J].中国组织工程研究与临床康复,2010,14(39):7367-7370.
[7] 王伟民,刘红军,石晶.关节镜联合应用盐酸氨基葡萄糖治疗轻中度骨性关节炎[J].临床骨科杂志,2013,16(1):114-115.
[8] 刘文成,黄相杰.中医药治疗膝骨性关节炎研究进展[J].中国中医骨伤科杂志,2016,24(12):79-82.
[9] 董天华.膝关节骨性关节炎的基础与临床研究[D].石家庄:河北医科大学,2016.
[10] 侯建鹏,刘鹏,姜胜峰,等.针药结合治疗膝关节骨性关节炎的临床研究进展[J].针灸临床杂志,2016,32(11):98-102.
[11] 冯志军.关节镜下膝关节清理术治疗膝骨性关节炎的进展[J].白求恩军医学院学报,2008(3):163-165.
[12] 田俊,袁风,何培,等.关节镜下治疗膝关节骨性关节炎[J].贵阳中医学院学报,2016,38(6):24-26.
[13] 苏晓琳,王江威,赵婉,等.独活寄生汤治疗膝骨性关节炎作用机制的研究进展[J].中国医药导报,2018,15(7):36-39.
[14] 卓金锁.中医综合疗法治疗膝骨性关节炎的临床研究[D].北京:北京中医药大学,2007.
[15] 贾俊骅,王仑,姜琳,等.伸筋草功效考[J].中国中医基础医学杂志,2017,23(6):861.
[16] 谭辉.中药透骨草的化学成分及药理活性探究[J].中国医药指南,2017,15(25):29-30.
[17] 刘婷,孙玉茹,秦彩玲,等.路路通酸的抗炎镇痛作用[J].中国实验方剂学杂志,2006(12):45-47.
[18] 张敏.威灵仙化学成分及生物活性研究进展[J].中国生化药物杂志,2015,35(7):165-168.
[19] 黄丽婵,杨世奎,刘发元,等.川牛膝、怀牛膝治疗骨关节炎的药效物质基础探讨[J].风湿病与关节炎,2014,3(11):52-54.
[20] 刘文成,黄相杰.中医药治疗膝骨性关节炎研究进展[J].中国中医骨伤科杂志,2016,24(12):79-82. |
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