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Advances in research on the relationship between stroke location and sleep disorders |
ZHANG Fang MAN Yuhong YAO Gang YU Tingmin |
Department of Neurology, the Second Hospital of Jilin University, Jilin Province, Changchun 130041, China |
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Abstract The occurrence and clinical manifestations of post-stroke sleep disorders are related to the injury site of stroke. Brain stem stroke leads to rapid eye movement sleep behavior disorder, sleep-disordered breathing, restless leg syndrome and periodic limb movement in sleep. Patients with thalamic stroke often show increased sleep. Hypothalamic stroke related sleep disorders manifest as somnolence and narcolepsy. Prefrontal cortical stroke causes insomnia. The regulation of the wake-sleep cycle depends on the anatomical and functional integrity of the cortical and subcortical neural networks. The mechanisms of post-stroke sleep disorders are mainly associated with the destruction of anatomical fibers and impaired neurotransmitter function after stroke in different locations. As post-stroke sleep disorders affect the improvement of neurological function, clinicians should pay attention to this as early as possible.
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