甲状腺结节的超声诊断特征分析与研究

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Abstract Objective To assess the value of ultrasonographic characteristics and thyroid imaging reporting and data system (TI-RADS) for qualitative diagnosis of thyroid nodules. Methods A total of 347 patients with thyroid nodules underwent surgical treatment in the Affiliated Huai′an No.1 Pecople′s Hospital of Nanjing Medical University from January to December 2016 were enrolled. All of the enrolled patients were divided into the benign group (n = 127) and the malignant group (n = 220) according to the postoperative pathological diagnosis results. The ultrasound imaging findings in the two groups were observed and compared. The patients were divided into 1 to 5 grades by TI-RADS classification standard, and the grading diagnosis results were compared with pathological diagnosis results. Results Of the 347 patients, there were 1 case of TI-RADS level 1, 54 cases of TI-RADS level 2, 59 cases of TI-RADS level 3, 51 cases of TI-RADS level 4a, 88 cases of TI-RADS level 4b, 68 cases of TI-RADS level 4c, 26 cases of TI-RADS level 5. Ultrasound images in the malignant group showed characteristics of irregular shape, unclear boundary, microcalcification, and abundant blood flow signals, the propotions of these characteristics were higher than those in the benign group, the differences were statistically significant (P ＜ 0.05). Among the 347 patients, using grade 4a as the criterion for classifying benign and malignant lesion, the specificity, sensitivity and accuracy of TI-RADS classification was 74.8%, 91.4% and 85.3%, respectively; if only grade 1-3 (representing benign lesion) and grade 4b-5 (representing malignant lesion) were considered, with exclusion of the dubious grade 4a, the specificity, sensitivity and accuracy of TI-RADS classification was 91.3%, 90.1% and 90.1%, respectively. Conclusion The sensitivity, specificity and accuracy of TI-RADS classification in diagnosis of thyroid cancer are high. The application of TI-RADS classification is helpful for clinicians to interpret the diagnostic evaluation of ultrasound and thereby to make a reasonable treatment plan. So it has great clinical practical value.

Key words： Thyroid nodule Thyroid cancer TI-RADS Ultrasonography Diagnosis

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	GUO Haowei ZHEN Linlin

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GUO Haowei ZHEN Linlin. Analysis and study of ultrasonographic characteristics of thyroid nodules[J]. 中国医药导报, 2019, 16(4): 149-152.

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http://www.yiyaodaobao.com.cn/EN/ OR http://www.yiyaodaobao.com.cn/EN/Y2019/V16/I4/149

[1] Burgess JR. Temporal trends for thyroid carcinoma in Australia：anincreasingincidence of papillary thyroid carcinoma（1982-1997）[J]. Thyroid，2002，12（2）：141-149.
[2] Horvath E，Majlis S，Rossi R，et al. An Ultrasonogram Reporting System for Thyroid Nodules Stratifying Cancer Risk for Clinical Management [J]. J Clin Endocrinol Metab，2009，94（5）：1748-1751.
[3] Park JY，Lee HJ，Jang HW，et al. A proposal for a thyroid imaging reporting and data system for ultrasound features of thyroid carcinoma [J]. Thyroid，2009，19（11）：1257-1264.
[4] 张波，徐景竹，吴琼.2015年美国甲状腺学会《成人甲状腺结节与分化型甲状腺癌诊治指南》解读：超声部分[J].中国癌症杂志，2016，26（1）：19-24. doi：10.3969/j.issn.1007-3969.2016.01.003.
[5] 王晓庆，魏玺，徐勇，等.良恶性甲状腺结节的超声征象及甲状腺影像报告和数据系统分级对甲状腺结节的诊断价值[J].中华肿瘤杂志，2015，37（2）：138-142.
[6] Hand HA，Cannon CR. Ultrasound-guided fine needle aspiration in the diagnosis of thyroid nodules [J]. J MissState Med Assoc，2014，55（9）：284-286.
[7] Chen W，Zheng R，Baade PD，et al. Cancer statistics in China，2015 [J]. CA Cancer J Clin，2016，66（2）：115-132．
[8] 钟敏莹，石小红，杨丽丽，等.TI-RADS分类系统对不同直径甲状腺结节的诊断价值[J].中国超声医学杂志，2016， 32（4）：289-291.
[9] 聂芳，汪延芳，耿祥亮，等.不同标准TI-RADS分级对甲状腺癌的价值探讨[J].中国超声医学杂志，2016，32（11）：967-970.
[10] 武文，朱洁，黄晓玲，等.甲状腺结节误诊病例的声像图研究[J].中国超声医学杂志，2010，26（11）：1043-1045.
[11] 甘科红，丛淑珍，冯占武，等.甲状腺结节性疾病超声弹性成像误诊原因分析[J].中国超声医学杂志，2011，27（6）：505-507.
[12] Wang N，Xu Y，Ge C，et al. Association of sonographically detected calcification with thyroid carcinoma [J]. Head & Neck，2006，28（12）：1077.
[13] Jin YK，Kim EK，Son EJ，et al. Papillary Thyroid Carcinoma Manifested Solely as Microcalcifications on Sonography [J]. AJR Am J Roentgenol，2007，189（1）：227-231.
[14] Hoang JK，Lee WK，Lee M，et al. US Features of thyroid malignancy：pearls and pitfalls [J]. Radiographics，2007， 27（3）：847-860.
[15] 王勇，郝玉芝，宋颖，等.甲状腺微小乳头状癌超声诊断研究[J].中国超声医学杂志，2009，25（5）：449-452.
[16] Campoy-Balbontin F，Jurado-Gómez C，Amador-Gil A. Benign and Malignant Thyroid Nodules：US Differentiation-Prospective Study [C]// Radiological Society of North America 2011 Scientific Assembly and Meeting，2011.
[17] 詹维伟.甲状腺结节的超声诊断进展[J].中华医学超声杂志：电子版，2011，8（6）：1170-1179.
[18] 马步云，Parajuly SS，彭玉兰，等.甲状腺影像报告和数据系统在超声检查甲状腺结节中的应用[J].中国普外基础与临床杂志，2011，18（8）：898-901.
[19] 詹维伟，徐上妍.甲状腺结节超声检查新进展[J].中华医学超声杂志：电子版，2013，10（2）：88-93.
[20] Schueller-Weidekamm C，Schueller G，Kaserer K，et al. Diagnostic value of sonography，ultrasound-guided fine-needle aspiration cytology，and diffusion-weighted MRI in the characterization of cold thyroid nodules [J]. Eur J Radiol，2010，73（3）：538-544.