常规超声联合经皮超声造影对乳腺癌前哨淋巴结的诊断价值

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Abstract Objective To investigate the diagnose value of conventional ultrasound combined with injected subcutaneously contrast-enhanced ultrasound (CEUS) in transferred sentinel lymph nodes (SLN) of breast cancer. Methods Taking the coarse needle biopsy results as a gold standard, the results of conventional ultrasound and CEUS of 101 SLNs in the ipsilateral axilla of 66 breast cancer patients from March to December 2017 in the Affiliated Hospital of North Sichuan Medical College were retrospectively analyzed and compared. Different perfusion methods of lymph nodes in CEUS were used for scoring. The two methods were analyzed by Logistic regression and receiver operating characteristic (ROC) curve. Z test was used to evaluate the curve, McNemar test was used to compare the results of the two methods. The cut-off value was determined according to the ROC curve of CEUS and SLNs were assessed. Results The area under the ROC curve of the two methods was compared, the area under the ROC curve of conventional ultrasound was 0.779 and contrast-enhanced ultrasound was 0.772, the difference was not statistically significant (P ＞ 0.05). The conventional ultrasound′s sensitivity, specificity and coincidence rate were 51.11%, 89.47%, 72.55% respectively. The CEUS′s sensitivity, specificity, coincidence rate were 46.67%, 93.1%, 72.82% respectively, there was no significant difference among the indicators (P ＞ 0.05). From CEUS′s ROC curve, the cut off value can help to evaluate the benign and malignant SLN. Conclusion Subcutaneously contrast-enhanced ultrasound has a high practical value in evaluating the benign and malignant SLN, and it is a powerful supplement to axillary lymph nodes detected by conventional ultrasound.

Key words： Breast cancer Contrast-enhanced ultrasound Sentinel lymph node Needle biopsy

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	WANG Ping LIU Jian LUO Yuqun LI Wenyan LI Zukun

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WANG Ping LIU Jian LUO Yuqun LI Wenyan LI Zukun. The diagnose value of conventional ultrasound combined with injected subcutaneously contrast-enhanced ultrasound in sentinel lymph nodes of breast cancer[J]. 中国医药导报, 2019, 16(4): 145-148.

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http://www.yiyaodaobao.com.cn/EN/ OR http://www.yiyaodaobao.com.cn/EN/Y2019/V16/I4/145

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