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| Effect of painless sedation and anesthesia on blood pressure in patients with hypertension by endobronchial ultrasound-guided transbronchial needle aspiration biopsy |
| JING Fa YANG Jian ZHU Ying YANG Yang WU Liangquan ZHANG Qiao LIU Panpan ZHANG Xiuwei |
| Department of Respiratory Medicine, the Affiliated Jiangning Hospital of Nanjing Medical University, Jiangsu Province, Nanjing 211100, China |
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Abstract Objective To observe the effect of painless sedation and anesthesia on blood pressure in patients with hypertension by endobronchial ultrasound-guided transbronchial needle aspiration biopsy (EBUS-TBNA). Methods From January 2016 to December 2017, 70 cases of hypertension patients with mediastinal and hilar occupying lesions on chest enhanced CT admitted to the Department of Respiratory Medicine of Jiangning Hospital Affiliated to Nanjing Medical University were selected. EBUS-TBNA examination was performed in 40 patients under painless sedation and anesthesia (PR group, n = 40), and EBUS-TBNA examination was performed in 30 patients under local anesthesia (L group, n = 30). The changes of blood pressure, heart rate and blood oxygen saturation in the two groups were observed when the two anesthesia methods were used for examination, and the anesthetic effect, subjective feelings and adverse reactions of the patients in the examination were evaluated. Results Blood pressure of patients in the L group increased during and after examination compared with that before anesthesia, and the difference was statistically significant (P ＜ 0.05). The blood pressure of patients in the PR group decreased during and after the examination compared with that before anesthesia, and the difference was statistically significant (P ＜ 0.05). The anesthesia effect of PR group was significantly better than that of L group, the diagnosis rate was significantly higher than that of L group, and the satisfaction rate of sampling was significantly lower than that of L group, the difference was statistically significant (P ＜ 0.05). Bradycardia was more common in PR group than in L group, and no other serious complications were found in both groups. Conclusion Compared with local anesthesia, painless sedation anesthesia can significantly reduce patients′ intraoperative or postoperative blood pressure, which is more suitable for ebus-tbna examination in patients with hypertension.
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