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Research progress on mechanism of tension-type headache |
SUN Yongxin1,2 YAO Gang1 YU Tingmin1 MAN Yuhong1 |
1.Department of Neurology, the Second Hospital of Jilin University, Jilin Province, Changchun 130041, China;
2.Second Clinial College, Jilin University, Jilin Province, Changchun 130041, China |
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Abstract Tension-type headache (TTH) is the most common type of primary headache, which is still lacking enough attention. Factors such as peripheral sensitization, craniocerebral muscle tenderness and abnormal muscle activity, abnormal regulation mechanism of central nervous system pain, cytokines and metabolic disorders of inflammatory mediators may participate in the pathogenesis of TTH from different aspects. Electrophysiological techniques, neuroimaging techniques and testing techniques provide an effective means for the study of the pathogenesis of TTH. This article briefly summarizes the possible pathogenesis of TTH and the corresponding research progress, in order to deepen the understanding of this disease, and provide reference for basic research and clinical diagnosis and treatment.
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